enQuire Bio » Products » Antibody » Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Ultraspecific Antibody Tested against >20,000 Human Proteins
Analysis of Protein Array containing >19,000 full-length human proteins using Elastin (ELN) Mouse Monoclonal Antibody (ELN/1981) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Analysis of Protein Array containing >19,000 full-length human proteins using Elastin (ELN) Mouse Monoclonal Antibody (ELN/1981) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.SDS-PAGE Analysis Purified Elastin Mouse Monoclonal Antibody (ELN/1981) Confirmation of Integrity and Purity of Antibody.

Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 199.00 – $ 429.00
Please Select Product Options Below To View The Catalog Number.

SKU: 2006-MSM1
Species: Human
Tested Applications: IHC, ELISA
Available Conjugates: Unconjugated
Isotype: Mouse IgG1, kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
2006-MSM1-P0 Size: 20 ug, Tag: Unconjugated $ 228.00
2006-MSM1-P1 Size: 100 ug, Tag: Unconjugated $ 488.00
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SKU: 2006-MSM1-P0
Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) General Information
Alternate Names
Elastin; ELN; SVAS; Tropoelastin; WBS; WS
Molecular Weight
70kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol 2006
Entrez Gene ID ELN
UniProt ID(s) P15502
UniGene ID(s) Hs647061
COSMIC ID Link(s) ELN
KEGG Gene ID(s) hsa:2006
General Description of Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis).
Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Human Anti-Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody Product Attributes

Species: Human
Tested Applications: IHC, ELISA.
Clonality: Monoclonal
Anti-Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody Clone: ELN/1981
Clone ELN/1981 Host and Isotype: Mouse IgG1, kappa
Anti-Human Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Positive Control Sample: A549 or U-2197cells. Liver, Kidney, Lung or Intestine.
Cellular Localization of Antibody ELN/1981 Staining: Secreted and Extracellular Space
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant full-length human Elastin protein
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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