Analysis of Protein Array containing >19,000 full-length human proteins using IgG Recombinant Mouse Monoclonal Antibody (rIG266) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Analysis of Protein Array containing >19,000 full-length human proteins using IgG Recombinant Mouse Monoclonal Antibody (rIG266) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.SDS-PAGE Analysis Purified IgG Mouse Recombinant Monoclonal Antibody (rIG266).Confirmation of Purity and Integrity of Antibody.

IgG Heavy Chain (B-Cell Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 228.00$ 488.00
Please Select Product Options Below To View The Catalog Number.

SKU: 3500-MSM10
Species: Human
Tested Applications: Flow, IF, IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG1
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 3500-MSM10-P0
IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) General Information
Alternate Names
G1m Marker, G2m Marker, G3m Marker, G4m Marker, HDC, Heavy Chain Disease Protein, Human Immunglobulin G, Ig gamma1, Ig gamma 2, Ig gamma 3, Ig gamma 4, Chain C Region, IGHG1, IGHG2, IGHG3, IGHG4
Molecular Weight
75kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol3500 (IGHG1), 3501 (IGHG2), 3502 (IGHG3), 3503 (IGHG4) (Human)
Entrez Gene IDIGHG
UniProt ID(s)P01857, P01859, P01860, P01861
UniGene ID(s)Hs510635
COSMIC ID Link(s)IGHG
KEGG Gene ID(s)hsa:3500 (IGHG1), 3501 (IGHG2), 3502 (IGHG3), 3503 (IGHG4) (Human)
General Description of IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker).
Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Human Anti-IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Antibody Product Attributes

Species: Human
Tested Applications: Flow, IF, IHC.
Clonality: Monoclonal
Anti-IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Antibody Clone: rIG266
Clone rIG266 Host and Isotype: Mouse IgG1
Anti-Human IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Positive Control Sample: 293T, Raji or hPBL cells. Tonsil or Spleen.
Cellular Localization of Antibody rIG266 Staining: Cytoplasm, Cell Surface and Secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Purified human Ig Gamma Chain
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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IgG Heavy Chain (B-Cell Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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