enQuire Bio » Products » Antibody » Ki-67 (Proliferating Cell Marker) Ultraspecific Antibody Tested against >20,000 Human Proteins
Analysis of Protein Array containing more than 19,000 full-length human proteins using Ki67 Mouse Monoclonal Antibody (MKI67/2465).Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Ki67 Mouse Monoclonal Antibody (MKI67/2465).Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.SDS-PAGE Analysis Purified Ki67 Mouse Monoclonal Antibody (MKI67/2465).Confirmation of Integrity and Purity of Antibody.

Ki-67 (Proliferating Cell Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 199.00 – $ 429.00
Please Select Product Options Below To View The Catalog Number.

SKU: 4288-MSM5
Species: Human
Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b, kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
4288-MSM5-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
4288-MSM5-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
4288-MSM5-P1ABX Size: 100 ug, Tag: Unconjugated $ 429.00
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SKU: 4288-MSM5-P0
Ki-67 (Proliferating Cell Marker) General Information
Alternate Names
KI-67; Ki67; KI-67 Antigen (KIA); MKI67; Proliferation related Ki-67 antigen
Molecular Weight
345kDa and 395kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol4288
Entrez Gene IDMKI67
UniProt ID(s)P46013
UniGene ID(s)Hs689823
COSMIC ID Link(s)MKI67
KEGG Gene ID(s)hsa:4288
General Description of Ki-67 (Proliferating Cell Marker).
Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.

Human Anti-Ki-67 (Proliferating Cell Marker) Antibody Product Attributes

Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-Ki-67 (Proliferating Cell Marker) Antibody Clone: MKI67/2465
Clone MKI67/2465 Host and Isotype: Mouse IgG2b, kappa
Anti-Human Ki-67 (Proliferating Cell Marker) Positive Control Sample: Any actively proliferating cells. Skin, Tonsil or Lymph Node
Cellular Localization of Antibody MKI67/2465 Staining: Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment of human Ki67 protein (apprx. aa 2293-2478) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

Ki-67 (Proliferating Cell Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, Ki-67 (Proliferating Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Ki-67 (Proliferating Cell Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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