Western Blot Analysis of human A431 cell lysate using MTAP Mouse Monoclonal Antibody (MTAP/1813).
Western Blot Analysis of human A431 cell lysate using MTAP Mouse Monoclonal Antibody (MTAP/1813).Analysis of Protein Array containing more than 19,000 full-length human proteins using MTAP Mouse Monoclonal Antibody (MTAP/1813).Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.SDS-PAGE Analysis Purified MTAP Mouse Monoclonal Antibody (MTAP/1813).Confirmation of Integrity and Purity of Antibody.

MTAP (Tumor Suppressor Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 228.00$ 488.00
Please Select Product Options Below To View The Catalog Number.

SKU: 4507-MSM1
Species: Human
Tested Applications: ELISA, WB, IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b, kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
4507-MSM1-P0 Size: 20 ug, Tag: Unconjugated $ 228.00
4507-MSM1-P1 Size: 100 ug, Tag: Unconjugated $ 488.00
4507-MSM1-P1ABX Size: 100 ug, Tag: Unconjugated $ 488.00
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
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SKU: 4507-MSM1-P0
MTAP (Tumor Suppressor Marker) General Information
Alternate Names
BDMF; DMSFH; DMSMFH; Epididymis luminal protein 249; HEL249; LGMBF; MeSAdo phosphorylase; Methylthioadenosine phosphorylase; MSAP; MTA phosphorylase; MTAP; MTAPase; S-methyl-5''-thioadenosine phosphorylase
Molecular Weight
31kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol4507
Entrez Gene IDMTAP
UniProt ID(s)Q13126
UniGene ID(s)Hs193268
COSMIC ID Link(s)MTAP
KEGG Gene ID(s)hsa:4507
General Description of MTAP (Tumor Suppressor Marker).
Recognizes a protein of 31kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.

Human Anti-MTAP (Tumor Suppressor Marker) Antibody Product Attributes

Species: Human
Tested Applications: ELISA, WB, IHC.
Clonality: Monoclonal
Anti-MTAP (Tumor Suppressor Marker) Antibody Clone: MTAP/1813
Clone MTAP/1813 Host and Isotype: Mouse IgG2b, kappa
Anti-Human MTAP (Tumor Suppressor Marker) Positive Control Sample: HepG2, A431, HeLa or MCF-7 cells. Kidney
Cellular Localization of Antibody MTAP/1813 Staining: Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant human MTAP protein fragment (aa97-196) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

MTAP (Tumor Suppressor Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, MTAP (Tumor Suppressor Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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MTAP (Tumor Suppressor Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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