Data from SDS-PAGE analysis of Anti-Olig2 antibody (Clone OLIG2/2400). Reducing lane (R) shows heavy and light chain fragments. NR lane shows intact antibody with expected MW of approximately 150 kDa. The data are consistent with a high purity, intact mAb.Analysis of Protein Array containing >19,000 full-length human proteins using OLIG2 Mouse Monoclonal Antibody (OLIG2/2400) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

OLIG2 (Marker of Glial Brain Tumors) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 199.00$ 429.00
Please Select Product Options Below To View The Catalog Number.

SKU: 10215-MSM1
Species: Human
Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG1, kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
10215-MSM1-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
10215-MSM1-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
10215-MSM1-P1ABX Size: 100 ug, Tag: Unconjugated $ 429.00
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SKU: 10215-MSM1-P0
OLIG2 (Marker of Glial Brain Tumors) General Information
Alternate Names
Basic helix loop helix protein class B1 (bHLHB1); basic helix-loop-helix protein 19 (bHLHe19); OLIG2; Oligodendrocyte lineage transcription factor 2; Oligodendrocyte specific bHLH transcription factor 2; Oligodendrocyte transcription factor 2; Protein kinase C-binding protein 2 (PRKCBP2); RACK17
Molecular Weight
30-40kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol10215
Entrez Gene IDOLIG2
UniProt ID(s)Q13516
UniGene ID(s)Hs176977
COSMIC ID Link(s)OLIG2
KEGG Gene ID(s)hsa:10215
General Description of OLIG2 (Marker of Glial Brain Tumors).
Olig2, a basic helix-loop-helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuro-epithelial tumors, ependymomas, sub-ependymomas, medulloblastomas, and non-neuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid / rhabdoid tumor, and haemangioblastomas. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue (gliosis).

Human Anti-OLIG2 (Marker of Glial Brain Tumors) Antibody Product Attributes

Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-OLIG2 (Marker of Glial Brain Tumors) Antibody Clone: OLIG2/2400
Clone OLIG2/2400 Host and Isotype: Mouse IgG1, kappa
Anti-Human OLIG2 (Marker of Glial Brain Tumors) Positive Control Sample: THP-1 cells. Astrocytoma
Cellular Localization of Antibody OLIG2/2400 Staining: Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment of human OLIG2 protein (apprx. aa 1-141) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

OLIG2 (Marker of Glial Brain Tumors) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, OLIG2 (Marker of Glial Brain Tumors) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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OLIG2 (Marker of Glial Brain Tumors) Ultraspecific Antibody

Tested against >20,000 Human Proteins

https://enquirebio.com/wp-content/uploads/2019/01/Anti-Olig2 Specificity Assay (Array)-300x120.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Olig2 IHC human Cerebellum (OLIG2 2400)-300x225.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Anti-Olig2(OLIG2 2400) Gel-228x300.jpghttps://enquirebio.com/wp-content/uploads/2018/06/enQuire-Bio-10215-MSM1-P0-anti-OLIG2-Marker-of-Glial-Brain-Tumors-antibody-1-300x120.jpeg