enQuire-Bio-55-MSM4-P0-anti-Prostate-Specific-Acid-Phosphatase-PSAP-antibody

Prostate Specific Acid Phosphatase (PSAP) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 158.00$ 348.00
Please Select Product Options Below To View The Catalog Number.

SKU: 55-MSM4
Species: Human
Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG1, kappa
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 55-MSM4-P0
Prostate Specific Acid Phosphatase (PSAP) General Information
Alternate Names
5'-nucleotidase (5'-NT); Acid phosphatase prostate; ACP3; Ecto-5'-nucleotidase; Prostatic acid phosphatase (PAP); Prostatic acid phosphatase; Thiamine monophosphatase (TMPase)
Molecular Weight
52kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol55
Entrez Gene IDACPP
UniProt ID(s)P15309
UniGene ID(s)Hs433060
COSMIC ID Link(s)ACPP
KEGG Gene ID(s)hsa:55
General Description of Prostate Specific Acid Phosphatase (PSAP).
Recognizes a protein of 52kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.

Human Anti-Prostate Specific Acid Phosphatase (PSAP) Antibody Product Attributes

Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-Prostate Specific Acid Phosphatase (PSAP) Antibody Clone: rACPP/1338
Clone rACPP/1338 Host and Isotype: Mouse IgG1, kappa
Anti-Human Prostate Specific Acid Phosphatase (PSAP) Positive Control Sample: PC12 cells or normal prostate or prostate carcinoma
Cellular Localization of Antibody rACPP/1338 Staining: Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant full-length human ACPP protein
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

Prostate Specific Acid Phosphatase (PSAP) Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Type:

Variations in PSAP antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in glandular cells in the prostate. More moderate antibody staining intensity was present in glandular cells in the prostate. Low, but measureable presence of PSAP could be seen in. We were unable to detect PSAP in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Observed Antibody Staining Data By Tissue Disease Status:

Tissues from cancer patients, for instance, have their own distinct pattern of PSAP expression as measured by anti-PSAP antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.

Sample Type breast cancer carcinoid cervical cancer colorectal cancer endometrial cancer glioma head and neck cancer liver cancer lung cancer lymphoma melanoma ovarian cancer pancreatic cancer prostate cancer renal cancer skin cancer stomach cancer testicular cancer thyroid cancer urothelial cancer
Signal Intensity - - - - - - - - - - - - - +++ - - - - - -
ACPP Variability + + + + + + + + + + + + + + + + + + + +

Limitations and Warranty

enQuire Bio's product, Prostate Specific Acid Phosphatase (PSAP) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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Prostate Specific Acid Phosphatase (PSAP) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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