Vinculin (Marker of Age-related Macular Degeneration) MonoSpecific Antibody
$ 199.00 – $ 429.00
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Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG1, kappa
Mass Spec Validated?: Not MS Validated
Datasheets and Documentation
|Vinculin (Marker of Age-related Macular Degeneration) General Information|
|CMD1W; CMH15; Epididymis luminal protein 114; HEL114; Metavinculin; MV; MVCL; VCL; VINC; Vinculin|
|Ships on blue ice.|
|Curated Database and Bioinformatic Data|
|Entrez Gene ID||VCL|
|COSMIC ID Link(s)||VCL|
|KEGG Gene ID(s)||hsa:7414|
|General Description of Vinculin (Marker of Age-related Macular Degeneration).|
|Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including Talin and Î±-Actinin. In addition, vinculin, Talin and Î±-Actinin each contain Actin binding sites. Expression of vinculin and Talin have been shown to be affected by the level of Actin expression. Î±-Actinin has been shown to link Actin to integrins in the plasma membrane through interactions with the vinculin and Talin complex or by a direct interaction with integrin.|
Tested Applications: IHC.
Anti-Vinculin (Marker of Age-related Macular Degeneration) Antibody Clone: VCL/2572
Clone VCL/2572 Host and Isotype: Mouse IgG1, kappa
Anti-Human Vinculin (Marker of Age-related Macular Degeneration) Positive Control Sample: Human Bladder and Testis.
Cellular Localization of Antibody VCL/2572 Staining: Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment of human Vinculin (VCL) protein (apprx. aa 174-322) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
enQuire Bio's product, Vinculin (Marker of Age-related Macular Degeneration) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.