Recombinant Human HBEGF / DTR Protein

$ 69.00 – $ 1,298.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5305
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 87

Product Number	Description	Price
QP5305-10ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 69.00
QP5305-50ug	Size: 50 ug, Tag: Untagged (Native Protein)	$ 169.00
QP5305-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 299.00
QP5305-500ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 759.00
QP5305-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 1,298.00

Shipping Information

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5305-50ug

Recombinant Human HBEGF / DTR Protein General Information
Alternate Names
HBEGF, DTR Protein, HEGFL, DTSF, DTR, DTS
Curated Database and Bioinformatic Data
Gene Symbol	HBEGF
Entrez Gene ID	1839
Ensemble Gene ID	ENSG00000113070
RefSeq Protein Accession(s)	NP_001936.1
RefSeq mRNA Accession(s)	NM_001945.2
UniProt ID(s)	Q99075
UniGene ID(s)	Hs.592942
HGNC ID(s)	HGNC:3059
COSMIC ID Link(s)	HBEGF
KEGG Gene ID(s)	hsa:1839
PharmGKB ID(s)	PA27513
General Description of Recombinant Human HBEGF / DTR Protein .
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the epidermal growth factor (EGF) family and is expressed by monocytes and macrophages. HB-EGF is the predominant growth factor involved in epithelialization during wound healing. HB-EGF signals through the receptor tyrosine kinase ErbB2 to maintain adult heart homeostasis, and promotes cardiac valve development through binding in high affinity to the epidermal growth factor receptor (EGFR). HB-EGF binds the the ErbB4 receptor tyrosine kinase to mediate implantation of the human blastocyst. HB-EGF also functions as a potent mitogen for fibroblasts and smooth muscle cells.

Human HBEGF / DTR Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant HBEGF / DTR based upon sequence from: Human

Host: QP5305 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5305.

Bioactivity Data: 3T3 cell proliferation is significantly induced by less than 1 ng/ml Human HBEGF / DTR, (activity greater than 1.0 x 10^6 units/mg).

Monomer or Dimer: Monomer

Amino Acid Sequence: MDLQEADLDL Â LRVTLSSKP QÂ ALATPNKE EHÂ GKRKKKG KGLÂ GKKRDP CLRKÂ YKDFC IHGECÂ KYVK ELRAPSÂ CIC HPGYHGERCH GLSL

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human HBEGF / DTR Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: 10 mM sodium phosphate, pH 7.5

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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