Recombinant Human Interleukin-21 / IL-21 Protein

$ 69.00 – $ 4,898.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5394
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 132

Product Number	Description	Price
QP5394-2ug	Size: 2 ug, Tag: Untagged (Native Protein)	$ 69.00
QP5394-10ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 169.00
QP5394-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 639.00
QP5394-500ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 2,978.00
QP5394-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 4,898.00

Shipping Information

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5394-10ug

Recombinant Human Interleukin-21 / IL-21 Protein General Information
Alternate Names
Interleukin-21, IL-21 Protein, CVID11, IL-21, Za11
Curated Database and Bioinformatic Data
Gene Symbol	IL21
Entrez Gene ID	59067
Ensemble Gene ID	ENSG00000138684
RefSeq Protein Accession(s)	NP_001193935.1
RefSeq mRNA Accession(s)	NM_001207006.2, NM_021803.3
UniProt ID(s)	Q9HBE4
UniGene ID(s)	Hs.567559
HGNC ID(s)	HGNC:6005
COSMIC ID Link(s)	IL21
KEGG Gene ID(s)	hsa:59067
PharmGKB ID(s)	PA29820
General Description of Recombinant Human Interleukin-21 / IL-21 Protein .
Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells and is aberrantly expressed in Hodgkin lymphoma cells. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. Within the B cell lineage, IL-21 is a switch factor regulating IgG1 and IgG3 antibody production. IL-21 also cooperates with IL-4 for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells.

Human Interleukin-21 / IL-21 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant Interleukin-21 / IL-21 based upon sequence from: Human

Host: QP5394 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5394.

Bioactivity Data: Measured by mino cell proliferation.

Monomer or Dimer: Monomer

Amino Acid Sequence: MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human Interleukin-21 / IL-21 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: 10 mM sodium phosphate, pH 7.5

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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