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Human LILRB4 / CD85k / ILT3 Bioactive Protein

$ 179.00$ 499.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP2848
Species: Human
Applications: Bioactive
Available Tags: C-terminal Fc
Host: Human
Purity: > 95 % as determined by SDS-PAGE.
Length (Amino Acids): 259

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Shipping Information
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Datasheets and Documentation
Product Datasheet
SKU: QP2848-100ug
Recombinant Human LILRB4 / CD85k / ILT3 Protein (Fc Tag) General Information
Alternate Names
CD85K, ILT-3, ILT3, LIR-5, LIR5, CD85K protein, ILT-3 protein, ILT3 protein, LIR-5 protein, LIR5 protein
Curated Database and Bioinformatic Data
Gene SymbolLILRB4
UniProt ID(s)AAH26309
COSMIC ID Link(s)LILRB4
General Description of Recombinant Human LILRB4 / CD85k / ILT3 Protein (Fc Tag).
LILRB4 is a member of the subclass B class of the leukocyte immunoglobulin-like receptor (LIR) family of protiens. LILRB4 activity is regulated by two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells and binds MHC class I molecules on antigen-presenting cells which activates a regulatory signaling cascade that inhibits stimulation of immune responses. LILRB4 can also impact antigen capture and presentation. It is thought to be an important constuent in regulatory responses that limit autoimmune responses via its role in limiting cytotoxic and inflammatory immune responses.

Human LILRB4 / CD85k / ILT3 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant LILRB4 / CD85k / ILT3 based upon sequence from: Human
Host: QP2848 protein expressed in Human.
Tag: C-terminal Fc
Protein Construction: A DNA sequence encoding the mature form of human LILRB4 (NP_001265356.2) (Met1-His257) was expressed with the Fc region of human IgG1 at the C-terminus.
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP2848.
Bioactivity Data: Tested by its ability to bind ANGPTL7 over a linear range of 0.03-0.5 pg/ml of LILRB4.
Full Length? Full Length Mature Form
Expression Region: Met1 - Glu259
Amino Acid Sequence: MIPTFTALLC LGLSLGPRTD MQAGPLPKPT LWAEPGSVIS WGNSVTIWCQ GTLEAREYRL DKEESPAPWD RQNPLEPKNK ARFSIPSMTE DYAGRYRCYY RSPVGWSQPS DPLELVMTGA YSKPTLSALP SPLVTSGKSV TLLCQSRSPM DTFLLIKERA AHPLLHLRSE HGAQQHQAEF PMSPVTSVHG GTYRCFSSHG FSHYLLSHPS DPLELIVSGS LEGPRPSPTR SVSTAAGPED QPLMPTGSVP HSGLRRHWE
Purity: > 95 % as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human LILRB4 / CD85k / ILT3 Protein:
Endotoxin Levels:
Buffer: TBS with 100 mM Glycine pH 7.0.
Storage Conditions: The protein should be aliquoted and stored under sterile conditions at -20 C short-term and -70 C for periods longer than one month. Avoid repeated freeze-thaw cycles.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Human LILRB4 / CD85k / ILT3 Bioactive Protein