Recombinant Mouse PDGFA Protein

$ 69.00 – $ 3,598.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5462
Species: Mouse
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 126/252

Product Number	Description	Price
QP5462-2ug	Size: 2 ug, Tag: Untagged (Native Protein)	$ 69.00
QP5462-10ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 169.00
QP5462-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 469.00
QP5462-500ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 2,198.00
QP5462-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 3,598.00

Shipping Information

1-2 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5462-2ug

Recombinant Mouse PDGFA Protein General Information
Alternate Names
PDGF1, PDGF-A
Curated Database and Bioinformatic Data
Gene Symbol	PDGFA
Entrez Gene ID	18590
RefSeq Protein Accession(s)	NP_032834.1
RefSeq mRNA Accession(s)	NM_008808.3
UniProt ID(s)	P20033
UniGene ID(s)	Mm.2675
COSMIC ID Link(s)	PDGFA
KEGG Gene ID(s)	mmu:18590
General Description of Recombinant Mouse PDGFA Protein .
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by interleukin 1 (IL-1), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF?), transforming growth factor beta (TGF-?), and epidermal growth factor (EGF) signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b.

Mouse PDGFA Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant PDGFA based upon sequence from Mouse

Host: QP5462 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5462.

Bioactivity Data: 3T3 cell proliferation significantly induced by less than 10 ng/ml of Mouse PDGFA (activity of at least 1.0 x 10^5 units/ml).

Monomer or Dimer: Dimer

Amino Acid Sequence: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATSNLN PDHREEETGR RRESGKNRKR KRLKPT

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.

Concentration of Mouse PDGFA Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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