Recombinant Human Osteonectin / SPARC Protein

$ 98.00 – $ 918.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP10176
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 326

Product Number	Description	Price
QP10176-ec-10ug	Size: 10 ug, Tag: His	$ 98.00
QP10176-ec-50ug	Size: 50 ug, Tag: His	$ 248.00
QP10176-ec-100ug	Size: 100 ug, Tag: His	$ 508.00
QP10176-ec-250ug	Size: 250 ug, Tag: His	$ 918.00

Shipping Information

7-10 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP10176-ec-10ug

Recombinant Human Osteonectin / SPARC Protein General Information
Alternate Names
Osteonectin; SPARC; BM-40; ON; OI17
Curated Database and Bioinformatic Data
Gene Symbol	SPARC
Entrez Gene ID	6678
Ensemble Gene ID	ENSG00000113140
RefSeq Protein Accession(s)	NP_001296372.1
RefSeq mRNA Accession(s)	NM_001309443.1, NM_001309444.1, NM_003118.3
UniProt ID(s)	P09486
UniGene ID(s)	Hs.111779
HGNC ID(s)	HGNC:11219
COSMIC ID Link(s)	SPARC
KEGG Gene ID(s)	hsa:6678
PharmGKB ID(s)	PA36055
General Description of Recombinant Human Osteonectin / SPARC Protein.
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.

Human Osteonectin / SPARC Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant Osteonectin / SPARC based upon sequence from: Human

Host: QP10176 protein expressed in E. coli.

Tag: His

Protein Construction: A DNA sequence encoding the Human Osteonectin / SPARC, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP10176.

Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by its ability to inhibit the cell growth of Mv1Lu mink lung epithelial cells is less than 3.0 ug/mL, corresponding to a specific activity of > 333 IU/mg.

Full Length? Partial (see sequence information for more details).

Amino Acid Sequence: MSYYHHHHHH DYDIPTTENL YFQGAMGSAP QQEALPDETE VVEETVAEVT EVSVGANP VQVEVGEFDD GAEETEEEVV AENPCQNHHC KHGKVCELDE NN TPMCVC QDPTSCPAPI GEFEKVCSND NKTFDSSCHF FATKCTLEGT KKGH KLHL DYIGPCKYIP PCLDSELTEF PLRMRDWLKN VLVTLYERDE DNNLLT EK QKLRVKKIHE NEKRLEAGDH PVELLARDFE KNYNMYIFPV HWQFGQLD QHPIDGYLSH TELAPLRAPL IPMEHCTTRF FETCDLDNDK YIALDEWAGC FGIKQKDI DKDLVI

Purity: Greater than 95% as determined by SDS-PAGE and HPLC.

Reconstitution Instructions:

Concentration of Human Osteonectin / SPARC Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.

Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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