Recombinant Human CCL4 / MIP1B Protein

$ 98.00$ 1,838.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10227
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 69

Product NumberDescriptionPrice
QP10227-ec-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 248.00
QP10227-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 1,018.00
QP10227-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 1,838.00
QP10227-ec-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 98.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10227-ec-20ug
Recombinant Human CCL4 / MIP1B Protein General Information
Alternate Names
CCL4; MIP1B; ACT2; HC21; MIP1B1; AT744.1; G-26; MIP1B; SCYA4; LAG1; LAG-1; MIP-1-beta; SCYA2
Curated Database and Bioinformatic Data
Gene SymbolCCL4
Entrez Gene ID388372
Ensemble Gene IDENSG00000275302
RefSeq Protein Accession(s)NP_002975.1
RefSeq mRNA Accession(s)NM_002984.3, NM_207007.3
UniProt ID(s)P13236
UniGene ID(s)Hs.449862
HGNC ID(s)HGNC:10630
KEGG Gene ID(s)hsa:388372
PharmGKB ID(s)PA35563
General Description of Recombinant Human CCL4 / MIP1B Protein.
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

Human CCL4 / MIP1B Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant CCL4 / MIP1B based upon sequence from: Human
Host: QP10227 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CCL4 / MIP1B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10227.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using human CCR5 transfected murine BaF3 cells is less than 2.0 ng/ml, corresponding to a specific activity of > 5.0 × 105 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CCL4 / MIP1B Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human CCL4 / MIP1B Protein

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