Recombinant Human IL16 / Interleukin-16 Protein

$ 98.00 – $ 3,188.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP10304
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 121

Product Number	Description	Price
QP10304-ec-10ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 248.00
QP10304-ec-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 1,778.00
QP10304-ec-250ug	Size: 250 ug, Tag: Untagged (Native Protein)	$ 3,188.00
QP10304-ec-2ug	Size: 2 ug, Tag: Untagged (Native Protein)	$ 98.00

Shipping Information

7-10 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP10304-ec-10ug

Recombinant Human IL16 / Interleukin-16 Protein General Information
Alternate Names
IL16; Interleukin-16; prIL-16; NIL16; LCF; PRIL16
Curated Database and Bioinformatic Data
Gene Symbol	IL16
Entrez Gene ID	3603
Ensemble Gene ID	ENSG00000172349
RefSeq Protein Accession(s)	NP_001165599.1
RefSeq mRNA Accession(s)	NM_001172128.1, NM_004513.5, NM_172217.3, XM_005254346.4, XM_011521520.2, XM_017022141.1, XM_017022142.1
UniProt ID(s)	Q14005
UniGene ID(s)	Hs.459095
HGNC ID(s)	HGNC:5980
COSMIC ID Link(s)	IL16
KEGG Gene ID(s)	hsa:3603
PharmGKB ID(s)	PA29793
General Description of Recombinant Human IL16 / Interleukin-16 Protein.
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.; Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.; Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.

Human IL16 / Interleukin-16 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant IL16 / Interleukin-16 based upon sequence from: Human

Host: QP10304 protein expressed in E. coli.

Tag: Untagged

Protein Construction: A DNA sequence encoding the Human IL16 / Interleukin-16, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP10304.

Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human peripheral T Lymphocytes is in a concentration range of 50-500 ng/ml.

Full Length? Partial (see sequence information for more details).

Amino Acid Sequence: SAASASAASD VSVESTAEAT VCTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETVQPG DEILQLGGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QSKETTAAGD S

Purity: Greater than 95% as determined by SDS-PAGE and HPLC.

Reconstitution Instructions:

Concentration of Human IL16 / Interleukin-16 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.

Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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