Recombinant Human Plasminogen Protein

$ 98.00$ 578.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10364
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 259

Product NumberDescriptionPrice
QP10364-ec-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 98.00
QP10364-ec-50ug Size: 50 ug, Tag: Untagged (Native Protein) $ 248.00
QP10364-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 328.00
QP10364-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 578.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10364-ec-10ug
Recombinant Human Plasminogen Protein General Information
Curated Database and Bioinformatic Data
Gene SymbolPLG
Entrez Gene ID5340
Ensemble Gene IDENSG00000122194
RefSeq Protein Accession(s)NP_000292.1
RefSeq mRNA Accession(s)NM_000301.3
UniProt ID(s)P00747
HGNC ID(s)HGNC:9071
COSMIC ID Link(s)PLG
KEGG Gene ID(s)hsa:5340
PharmGKB ID(s)PA33405
General Description of Recombinant Human Plasminogen Protein.
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. ; Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.

Human Plasminogen Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant Plasminogen based upon sequence from: Human
Host: QP10364 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Plasminogen, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10364.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells in vitro and anti-angiogenesis in vivo is 5.5 × 105 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLK GTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGKRAPWCHT TNSQVRWEYC KIPSCDSSP
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Plasminogen Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 20 mM NaAc, pH 5.5, 4 % mannitol, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Plasminogen Protein

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