Human TRAIL R2 / CD262 / TNFRSF10B Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant TRAIL R2 / CD262 / TNFRSF10B based upon sequence from: Human
Host: QP10367 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human TRAIL R2 / CD262 / TNFRSF10B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10367.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. rHusTRAIL-R2 reduced the production of LPS- induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/mL) but in the presence of rHusTRAIL-R2, TRAIL-induced TNF is suppressed.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: ESALITQQDL APQQRAAPQQ KRSSPSEGLC PPGHHISEDG RDCISCKYGQ DYSTHWNDLL FCLRCTRCDS GEVELSPCTT TRNTVCQCEE GTFREEDSPE MCRKCRTGCP RGMVKVGDCT PWSDIECVHK ES
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human TRAIL R2 / CD262 / TNFRSF10B Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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