Recombinant Human FAS / CD95 / APO-1 / TNFRSF6 Protein

$ 98.00 – $ 1,858.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP10369
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 157

Product Number	Description	Price
QP10369-ec-5ug	Size: 5 ug, Tag: Untagged (Native Protein)	$ 98.00
QP10369-ec-20ug	Size: 20 ug, Tag: Untagged (Native Protein)	$ 248.00
QP10369-ec-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 1,058.00
QP10369-ec-250ug	Size: 250 ug, Tag: Untagged (Native Protein)	$ 1,858.00

Shipping Information

7-10 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP10369-ec-5ug

Recombinant Human FAS / CD95 / APO-1 / TNFRSF6 Protein General Information
Alternate Names
FAS; CD95; APO-1; TNFRSF6; CD95; FASTM; APO-1; ALPS1A; APT1; FAS1; TNFRSF6
Curated Database and Bioinformatic Data
Gene Symbol	FAS
Entrez Gene ID	355
Ensemble Gene ID	ENSG00000026103
RefSeq Protein Accession(s)	NP_000034.1
RefSeq mRNA Accession(s)	NM_000043.5, NM_001320619.1, NM_152871.3, NM_152872.3
UniProt ID(s)	P25445
UniGene ID(s)	Hs.244139
HGNC ID(s)	HGNC:11920
COSMIC ID Link(s)	FAS
KEGG Gene ID(s)	hsa:355
PharmGKB ID(s)	PA36613
General Description of Recombinant Human FAS / CD95 / APO-1 / TNFRSF6 Protein.
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Human FAS / CD95 / APO-1 / TNFRSF6 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant FAS / CD95 / APO-1 / TNFRSF6 based upon sequence from: Human

Host: QP10369 protein expressed in E. coli.

Tag: Untagged

Protein Construction: A DNA sequence encoding the Human FAS / CD95 / APO-1 / TNFRSF6, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP10369.

Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by its ability to inhibit the cytotoxicity of Jurkat cells is between 10-15 ug/ml in the presence of 2 ng/ml of rHuFas Ligand.

Full Length? Partial (see sequence information for more details).

Amino Acid Sequence: RLSSKSVNAQ VTDINSKGLE LRKTVTTVET QNLEGLHHDG QFCHKPCPPG ERKARDCTVN GDEPDCVPCQ EGKEYTDKAH FSSKCRRCRL CDEGHGLEVE INCTRTQNTK CRCKPNFFCN STVCEHCDPC TKCEHGIIKE CTLTSNTKCK EEGSRSN

Purity: Greater than 95% as determined by SDS-PAGE and HPLC.

Reconstitution Instructions:

Concentration of Human FAS / CD95 / APO-1 / TNFRSF6 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.

Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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