Recombinant Human TNFR1 / CD120a / TNFRSF1A Protein

$ 98.00 – $ 1,838.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP10374
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 190

Product Number	Description	Price
QP10374-ec-5ug	Size: 5 ug, Tag: Untagged (Native Protein)	$ 98.00
QP10374-ec-20ug	Size: 20 ug, Tag: Untagged (Native Protein)	$ 248.00
QP10374-ec-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 1,018.00
QP10374-ec-250ug	Size: 250 ug, Tag: Untagged (Native Protein)	$ 1,838.00

Shipping Information

7-10 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP10374-ec-5ug

Recombinant Human TNFR1 / CD120a / TNFRSF1A Protein General Information
Alternate Names
TNFR1; CD120a; TNFRSF1A; TNF-R55; TNF-alphaR1; Tnfr1; p55-R; FPF; TNFRp55; TNF-R; TNF-R-I; TNF-R1; TNFAR; TNFR60; TNFalpha-R1; Tnfr-2; p55; CD120a; TNFRI
Curated Database and Bioinformatic Data
Gene Symbol	TNFRSF1A
Entrez Gene ID	7132
Ensemble Gene ID	ENSG00000067182
RefSeq Protein Accession(s)	NP_001056.1
RefSeq mRNA Accession(s)	NM_001065.3, NM_001346091.1, NM_001346092.1
UniProt ID(s)	P19438
UniGene ID(s)	Hs.279594
HGNC ID(s)	HGNC:11916
COSMIC ID Link(s)	TNFRSF1A
KEGG Gene ID(s)	hsa:7132
PharmGKB ID(s)	PA36609
General Description of Recombinant Human TNFR1 / CD120a / TNFRSF1A Protein.
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

Human TNFR1 / CD120a / TNFRSF1A Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant TNFR1 / CD120a / TNFRSF1A based upon sequence from: Human

Host: QP10374 protein expressed in E. coli.

Tag: Untagged

Protein Construction: A DNA sequence encoding the Human TNFR1 / CD120a / TNFRSF1A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP10374.

Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 ug/ml, corresponding to a specific activity of > 2 Ã 104 IU/mg in the presence of 0.25 ng/mL of rHuTNF-alpha.

Full Length? Partial (see sequence information for more details).

Amino Acid Sequence: IYPSGVIGLV PHLGDREKRD SVCPQGKYIH PQNNSICCTK CHKGTYLYND CPGPGQDTDC RECESGSFTA SENHLRHCLS CSKCRKEMGQ VEISSCTVDR DTVCGCRKNQ YRHYWSENLF QCFNCSLCLN GTVHLSCQEK QNTVCTCHAG FFLRENECVS CSNCKKSLEC TKLCLPQIEN VKGTEDSGTT

Purity: Greater than 97% as determined by SDS-PAGE and HPLC.

Reconstitution Instructions:

Concentration of Human TNFR1 / CD120a / TNFRSF1A Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.

Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

There are no reviews yet.