Recombinant Human TNFR2 / CD120b / TNFRSF1B Protein

$ 98.00$ 1,838.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10375
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 184

Product NumberDescriptionPrice
QP10375-ec-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 98.00
QP10375-ec-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 248.00
QP10375-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 1,018.00
QP10375-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 1,838.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10375-ec-5ug
Recombinant Human TNFR2 / CD120b / TNFRSF1B Protein General Information
Alternate Names
TNFR2; CD120b; TNFRSF1B; p75; TNF-alphaR2; Tnfr2; TNF-R75; CD120b; TNFalpha-R2; TNF-R2; TNF-R-II; TNFRII; TNFBR; TNFR80; Tnfr-1
Curated Database and Bioinformatic Data
Gene SymbolTNFRSF1B
Entrez Gene ID7133
Ensemble Gene IDENSG00000028137
RefSeq Protein Accession(s)NP_001057.1
RefSeq mRNA Accession(s)NM_001066.2
UniProt ID(s)P20333
UniGene ID(s)Hs.256278
HGNC ID(s)HGNC:11917
COSMIC ID Link(s)TNFRSF1B
KEGG Gene ID(s)hsa:7133
PharmGKB ID(s)PA36610
General Description of Recombinant Human TNFR2 / CD120b / TNFRSF1B Protein.
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Human TNFR2 / CD120b / TNFRSF1B Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant TNFR2 / CD120b / TNFRSF1B based upon sequence from: Human
Host: QP10375 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human TNFR2 / CD120b / TNFRSF1B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10375.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.2 ug/ml, corresponding to a specific activity of > 5000 IU/mg in the presence of 0.25 ng/mL of rHuTNF-alpha.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: MPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH AKVFCTKTSD TVCDSCEDST YTQLWNWVPE CLSCGSRCSS DQVETQACTR EQNRICTCRP GWYCALSKQE GCRLCAPLRK CRPGFGVARP GTETSDVVCK PCAPGTFSNT TSSTDICRPH QICNVVAIPG NASMDAVCTS TSPT
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human TNFR2 / CD120b / TNFRSF1B Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human TNFR2 / CD120b / TNFRSF1B Protein