Recombinant Human Fibroblast growth factor 19 Protein

$ 98.00 – $ 1,428.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP10383
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 195

Product Number	Description	Price
QP10383-ec-5ug	Size: 5 ug, Tag: Untagged (Native Protein)	$ 108.00
QP10383-ec-25ug	Size: 25 ug, Tag: Untagged (Native Protein)	$ 278.00
QP10383-ec-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 918.00
QP10383-ec-250ug	Size: 250 ug, Tag: Untagged (Native Protein)	$ 1,598.00

Shipping Information

7-10 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP10383-ec-5ug

Recombinant Human Fibroblast growth factor 19 Protein General Information
Curated Database and Bioinformatic Data
Gene Symbol	FGF19
Entrez Gene ID	9965
Ensemble Gene ID	ENSG00000162344
RefSeq Protein Accession(s)	NP_005108.1
RefSeq mRNA Accession(s)	NM_005117.2
UniProt ID(s)	O95750
UniGene ID(s)	Hs.249200
HGNC ID(s)	HGNC:3675
COSMIC ID Link(s)	FGF19
KEGG Gene ID(s)	hsa:9965
PharmGKB ID(s)	PA28114
General Description of Recombinant Human Fibroblast growth factor 19 Protein.
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.

Human Fibroblast growth factor 19 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant Fibroblast growth factor 19 based upon sequence from: Human

Host: QP10383 protein expressed in E. coli.

Tag: Untagged

Protein Construction: A DNA sequence encoding the Human Fibroblast growth factor 19, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP10383.

Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 150 ng/ml, corresponding to a specific activity of > 6.7 Ã 103 IU/mg.

Full Length? Partial (see sequence information for more details).

Amino Acid Sequence: MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK

Purity: Greater than 95% as determined by SDS-PAGE and HPLC.

Reconstitution Instructions:

Concentration of Human Fibroblast growth factor 19 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.

Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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