Recombinant Human PDGF-B Protein

$ 98.00 – $ 2,398.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP10398
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 110

Product Number	Description	Price
QP10398-ec-2ug	Size: 2 ug, Tag: Untagged (Native Protein)	$ 98.00
QP10398-ec-10ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 248.00
QP10398-ec-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 1,328.00
QP10398-ec-250ug	Size: 250 ug, Tag: Untagged (Native Protein)	$ 2,398.00

Shipping Information

7-10 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP10398-ec-2ug

Recombinant Human PDGF-B Protein General Information
Alternate Names
PDGF-B; IBGC5; PDGF2; SSV; PDGF-2; SIS; c-sis
Curated Database and Bioinformatic Data
Gene Symbol	PDGFB
Entrez Gene ID	5155
Ensemble Gene ID	ENSG00000100311
RefSeq Protein Accession(s)	NP_002599.1
RefSeq mRNA Accession(s)	NM_002608.3, NM_033016.3
UniProt ID(s)	P01127
UniGene ID(s)	Hs.1976
HGNC ID(s)	HGNC:8800
COSMIC ID Link(s)	PDGFB
KEGG Gene ID(s)	hsa:5155
PharmGKB ID(s)	PA33145
General Description of Recombinant Human PDGF-B Protein.
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).

Human PDGF-B Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant PDGF-B based upon sequence from: Human

Host: QP10398 protein expressed in E. coli.

Tag: Untagged

Protein Construction: A DNA sequence encoding the Human PDGF-B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP10398.

Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 3 ng/ml, corresponding to a specific activity of > 3.3 Ã 105 IU/mg.

Full Length? Partial (see sequence information for more details).

Amino Acid Sequence: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT

Purity: Greater than 97% as determined by SDS-PAGE and HPLC.

Reconstitution Instructions:

Concentration of Human PDGF-B Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.

Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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