SDS-PAGE separation of QP5752 followed by commassie total protein stain results in a primary band consistent with reported data for CAMK4 / CaMKIV. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP5752 followed by commassie total protein stain results in a primary band consistent with reported data for CAMK4 / CaMKIV. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Rat CAMK4 / CaMKIV Protein

$ 648.00$ 2,768.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5752
Species: Rat
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 474

Product NumberDescriptionPrice
QP5752-ec-100ug Size: 100 ug, Tag: His $ 578.00
QP5752-ec-1mg Size: 1 mg, Tag: His $ 2,468.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5752-ec-10ug
Recombinant Rat CAMK4 / CaMKIV Protein General Information
Alternate Names
CAMK4, CaMKIV, AI666733, D18Bwg0362e, CaMKIV, CaMKIV/Gr, A430110E23Rik
Curated Database and Bioinformatic Data
Gene SymbolCamk4
Entrez Gene ID25050
Ensemble Gene IDENSRNOG00000020478
RefSeq Protein Accession(s)NP_036859.2
RefSeq mRNA Accession(s)NM_012727.3, XM_017600851.1
UniProt ID(s)P13234
UniGene ID(s)Rn.11046
COSMIC ID Link(s)Camk4
KEGG Gene ID(s)rno:25050
General Description of Recombinant Rat CAMK4 / CaMKIV Protein.
Isoform 1: Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and mory consolidation. In the thymus, regulates the CD4+/CD8+ double positive thymocytes selection threshold during T-cell ontogeny. In CD4 mory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2). Regulates the differentiation and survival phases of osteoclasts and dendritic cells (DCs). Mediates DCs survival by linking TLR4 and the regulation of tporal expression of BCL2. Phosphorylates the transcription activator CREB1 on 'Ser-133' in hippocampal neuron nuclei and contribute to mory consolidation and long term potentiation (LTP) in the hippocampus. Can activate the MAP kinases MAPK1/ERK2, MAPK8/JNK1 and MAPK14/p38 and stimulate transcription through the phosphorylation of ELK1 and ATF2. Can also phosphorylate in vitro CREBBP, PRM2, MEF2A and STMN1/OP18 .Isoform 2: Heat-stable, acidic, calmodulin-binding protein.

Rat CAMK4 / CaMKIV Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant CAMK4 / CaMKIV based upon sequence from Rat
Host: QP5752 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) CAMK4 / CaMKIV, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5752.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - Tyr474
Amino Acid Sequence: MLKVTVPSCP SSPCSSVTSS TENLVPDYWI DGSKRDPLSD FFEVESELGR GATSIVYRCK QKGTQKPYAL KVLKKTVDKK IVRTEIGVLL RLSHPNIIKL KEIFETPTEI SLVLELVTGG ELFDRIVEKG YYSERDAADA VKQILEAVAY LHENGIVHRD LKPENLLYAT PAPDAPLKIA DFGLSKIVEH QVLMKTVCGT PGYCAPEILR GCAYGPEVDM WSVGIITYIL LCGFEPFYDE RGDQFMFRRI LNCEYYFISP WWDEVSLNAK DLVKKLIVLD PKKRLTTFQA LQHPWVTGKA ANFVHMDTAQ KKLQEFNARR KLKAAVKAVV ASSRLGSASS SHTNIQESNK ASSEAQPAQD GKDKTDPLEN KMQAGDHEAA KAAADETMKL QSEEVEEEEG VKEEEEEEEE EEETSRMVPQ EPEDRLETDD QEMKRNSEET LKSVEEEMDP KAEEEAAAVG LGVPPQQDAI LPEY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Rat CAMK4 / CaMKIV Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Rat CAMK4 / CaMKIV Protein

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