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Recombinant Rat DPP4 / CD26 Protein

$ 728.00$ 2,468.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5944
Species: Rat
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 130

Product NumberDescriptionPrice
QP5944-ec-100ug Size: 100 ug, Tag: His-SUMO $ 728.00
QP5944-ec-1mg Size: 1 mg, Tag: His-SUMO $ 2,468.00
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2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5944-ec-10ug
Recombinant Rat DPP4 / CD26 Protein General Information
Alternate Names
DPP4, CD26, ADABP, TP103, DPPIV, ADCP2, CD26
Curated Database and Bioinformatic Data
Gene SymbolDpp4
Entrez Gene ID25253
RefSeq Protein Accession(s)NP_036921.1
RefSeq mRNA Accession(s)NM_012789.1
UniProt ID(s)P14740
UniGene ID(s)Rn.91364
COSMIC ID Link(s)Dpp4
KEGG Gene ID(s)rno:25253
General Description of Recombinant Rat DPP4 / CD26 Protein.
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the Extracellular domain matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

Rat DPP4 / CD26 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant DPP4 / CD26 based upon sequence from Rat
Host: QP5944 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) DPP4 / CD26, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5944.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser638 - Arg767
Amino Acid Sequence: SMVLGSGSGV FKCGIAVAPV SRWEYYDSVY TERYMGLPTP EDNLDHYRNS TVMSRAENFK QVEYLLIHGT ADDNVHFQQS AQISKALVDA GVDFQAMWYT DEDHGIASST AHQHIYSHMS HFLQQCFSLR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Rat DPP4 / CD26 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Rat DPP4 / CD26 Protein