SDS-PAGE separation of QP5964 followed by commassie total protein stain results in a primary band consistent with reported data for Ephrin-A1 / EFNA1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Rat Ephrin-A1 / EFNA1 Protein

$ 578.00 – $ 2,468.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5964
Species: Rat
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: E.coli, Yeast.
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 165

Product Number	Description	Price
QP5964-ec-100ug	Size: 100 ug, Tag: His	$ 578.00
QP5964-ec-1mg	Size: 1 mg, Tag: His	$ 2,468.00
QP5964-ye-100ug	Size: 100 ug, Tag: His	$ 578.00
QP5964-ye-1mg	Size: 1 mg, Tag: His	$ 2,468.00

Shipping Information

2-4 weeks

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5964-ec-10ug

Recombinant Rat Ephrin-A1 / EFNA1 Protein General Information
Alternate Names
Ephrin-A1, EFNA1, B61, ECKLG, EPLG1, LERK-1, EFL1, LERK1, TNFAIP4
Curated Database and Bioinformatic Data
Gene Symbol	EFNA1
Entrez Gene ID	94268
Ensemble Gene ID	ENSRNOG00000020573
RefSeq Protein Accession(s)	NP_446051.2
RefSeq mRNA Accession(s)	NM_053599.2
UniProt ID(s)	P97553
UniGene ID(s)	Rn.8427
COSMIC ID Link(s)	EFNA1
KEGG Gene ID(s)	rno:94268
General Description of Recombinant Rat Ephrin-A1 / EFNA1 Protein.
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assbly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of bryonic neuronal growth cone and regulates dendritic spine morphogenesis .

Rat Ephrin-A1 / EFNA1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Ephrin-A1 / EFNA1 based upon sequence from Rat

Host: QP5964 protein expressed in E.coli, Yeast..

Tag: His

Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) Ephrin-A1 / EFNA1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.

Application Notes: Please contact us for application specific information for QP5964.

Bioactivity Data: Untested

Full Length? Full Length

Expression Region: Ala18 - Ser182

Amino Acid Sequence: ADRHIVFWNS SNPKFREEDY TVHVQLNDYL DIICPHYEDD SVADAAMERY TLYMVEHQEY VTCEPQSKDQ VRWKCNQPSA KHGPEKLSEK FQRFTPFTLG KEFKEGHSYY YISKPIYHQE TQCLKLKVTV NGKITHSPHA HANPQEKRLQ ADDPEVQVLH SIGHS

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.

Concentration of Rat Ephrin-A1 / EFNA1 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

There are no reviews yet.