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Recombinant Human GAPDH Protein

$ 228.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6070
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 334

Product NumberDescriptionPrice
QP6070-ec-10ug Size: 10 ug, Tag: His-SUMO $ 228.00
QP6070-ec-50ug Size: 50 ug, Tag: His-SUMO $ 228.00
QP6070-ec-100ug Size: 100 ug, Tag: His-SUMO $ 398.00
QP6070-ec-200ug Size: 200 ug, Tag: His-SUMO $ 658.00
QP6070-ec-500ug Size: 500 ug, Tag: His-SUMO $ 1,098.00
QP6070-ec-1mg Size: 1 mg, Tag: His-SUMO $ 1,728.00
Shipping Information
1-2 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP6070-ec-10ug
Recombinant Human GAPDH Protein (2-335aa) General Information
Alternate Names
GAPDH, G3PD, HEL-S-162eP, GAPD
Curated Database and Bioinformatic Data
Gene SymbolGAPDH
Entrez Gene ID2597
Ensemble Gene IDENSG00000111640
RefSeq Protein Accession(s)NP_001243728.1
RefSeq mRNA Accession(s)NM_001256799.2, NM_001289745.1, NM_001289746.1, NM_002046.5
UniProt ID(s)P04406
UniGene ID(s)Hs.544577
HGNC ID(s)HGNC:4141
COSMIC ID Link(s)GAPDH
KEGG Gene ID(s)hsa:2597
PharmGKB ID(s)PA28554
General Description of Recombinant Human GAPDH Protein (2-335aa).
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Human GAPDH Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant GAPDH based upon sequence from Human
Host: QP6070 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GAPDH, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6070.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly2 - Glu335
Amino Acid Sequence: GKVKVGVNGF GRIGRLVTRA AFNSGKVDIV AINDPFIDLN YMVYMFQYDS THGKFHGTVK AENGKLVING NPITIFQERD PSKIKWGDAG AEYVVESTGV FTTMEKAGAH LQGGAKRVII SAPSADAPMF VMGVNHEKYD NSLKIISNAS CTTNCLAPLA KVIHDNFGIV EGLMTTVHAI TATQKTVDGP SGKLWRDGRG ALQNIIPAST GAAKAVGKVI PELNGKLTGM AFRVPTANVS VVDLTCRLEK PAKYDDIKKV VKQASEGPLK GILGYTEHQV VSSDFNSDTH SSTFDAGAGI ALNDHFVKLI SWYDNEFGYS NRVVDLMAHM ASKE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human GAPDH Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human GAPDH Protein