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Recombinant Human KCNJ10 Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6256
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 215

Product NumberDescriptionPrice
QP6256-ec-100ug Size: 100 ug, Tag: His-SUMO $ 398.00
QP6256-ec-1mg Size: 1 mg, Tag: His-SUMO $ 1,728.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP6256-ec-10ug
Recombinant Human KCNJ10 Protein General Information
Alternate Names
KIR4.1, KIR1.2, SESAME, KCNJ13-PEN, BIRK-10, ATP-sensitive inward rectifier potassium channel
Curated Database and Bioinformatic Data
Gene SymbolKCNJ10
Entrez Gene ID3766
Ensemble Gene IDENSG00000177807
RefSeq Protein Accession(s)NP_002232.2
RefSeq mRNA Accession(s)NM_002241.4
UniProt ID(s)P78508
UniGene ID(s)Hs.408960
HGNC ID(s)HGNC:6256
COSMIC ID Link(s)KCNJ10
KEGG Gene ID(s)hsa:3766
PharmGKB ID(s)PA30043
General Description of Recombinant Human KCNJ10 Protein.
May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of Extracellular domain potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by Extracellular domain barium and cesium .

Human KCNJ10 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant KCNJ10 based upon sequence from Human
Host: QP6256 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) KCNJ10, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6256.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Phe165 - Val379
Amino Acid Sequence: FLAKIARPKK RAETIRFSQH AVVASHNGKP CLMIRVANMR KSLLIGCQVT GKLLQTHQTK EGENIRLNQV NVTFQVDTAS DSPFLILPLT FYHVVDETSP LKDLPLRSGE GDFELVLILS GTVESTSATC QVRTSYLPEE ILWGYEFTPA ISLSASGKYI ADFSLFDQVV KVASPSGLRD STVRYGDPEK LKLEESLREQ AEKEGSALSV RISNV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human KCNJ10 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human KCNJ10 Protein