Recombinant Human Cytokeratin 18 Protein

$ 448.00 – $ 1,938.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP6278
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 420

Product Number	Description	Price
QP6278-ec-100ug	Size: 100 ug, Tag: His	$ 448.00
QP6278-ec-1mg	Size: 1 mg, Tag: His	$ 1,938.00

Shipping Information

2-4 weeks

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP6278-ec-10ug

Recombinant Human Cytokeratin 18 Protein (11-430aa) General Information
Alternate Names
Cytokeratin 18, CYK18, K18, CK-18
Curated Database and Bioinformatic Data
Gene Symbol	KRT18
Entrez Gene ID	3875
Ensemble Gene ID	ENSG00000111057
RefSeq Protein Accession(s)	NP_000215.1
RefSeq mRNA Accession(s)	NM_000224.2, NM_199187.1
UniProt ID(s)	P05783
UniGene ID(s)	Hs.406013
HGNC ID(s)	HGNC:6430
COSMIC ID Link(s)	KRT18
KEGG Gene ID(s)	hsa:3875
PharmGKB ID(s)	PA30217
General Description of Recombinant Human Cytokeratin 18 Protein (11-430aa).
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma mbrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection

Human Cytokeratin 18 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Cytokeratin 18 based upon sequence from Human

Host: QP6278 protein expressed in E. coli.

Tag: His

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Cytokeratin 18, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.

Application Notes: Please contact us for application specific information for QP6278.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Thr11 - His430

Amino Acid Sequence: TNYRSLGSVQ APSYGARPVS SAASVYAGAG GSGSRISVSR STSFRGGMGS GGLATGIAGG LAGMGGIQNE KETMQSLNDR LASYLDRVRS LETENRRLES KIREHLEKKG PQVRDWSHYF KIIEDLRAQI FANTVDNARI VLQIDNARLA ADDFRVKYET ELAMRQSVEN DIHGLRKVID DTNITRLQLE TEIEALKEEL LFMKKNHEEE VKGLQAQIAS SGLTVEVDAP KSQDLAKIMA DIRAQYDELA RKNREELDKY WSQQIEESTT VVTTQSAEVG AAETTLTELR RTVQSLEIDL DSMRNLKASL ENSLREVEAR YALQMEQLNG ILLHLESELA QTRAEGQRQA QEYEALLNIK VKLEAEIATY RRLLEDGEDF NLGDALDSSN SMQTIQKTTT RRIVDGKVVS ETNDTKVLRH

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.

Concentration of Human Cytokeratin 18 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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