SDS-PAGE separation of QP6367 followed by commassie total protein stain results in a primary band consistent with reported data for Collagenase 3. These data demonstrate Greater than 80% as determined by SDS-PAGE.
SDS-PAGE separation of QP6367 followed by commassie total protein stain results in a primary band consistent with reported data for Collagenase 3. These data demonstrate Greater than 80% as determined by SDS-PAGE.

Recombinant Human Collagenase 3 Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6367
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 368

Product NumberDescriptionPrice
QP6367-ec-100ug Size: 100 ug, Tag: His-SUMO $ 398.00
QP6367-ec-1mg Size: 1 mg, Tag: His-SUMO $ 1,728.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP6367-ec-10ug
Recombinant Human Collagenase 3 Protein General Information
Alternate Names
CLG3, MMP-13, MDST, MANDP1
Curated Database and Bioinformatic Data
Gene SymbolMMP13
Entrez Gene ID4322
Ensemble Gene IDENSG00000137745
RefSeq Protein Accession(s)NP_002418.1
RefSeq mRNA Accession(s)NM_002427.3
UniProt ID(s)P45452
UniGene ID(s)Hs.2936
HGNC ID(s)HGNC:7159
COSMIC ID Link(s)MMP13
KEGG Gene ID(s)hsa:4322
PharmGKB ID(s)PA30871
General Description of Recombinant Human Collagenase 3 Protein.
Plays a role in the degradation of Extracellular domain matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue rodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal bryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.

Human Collagenase 3 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Collagenase 3 based upon sequence from Human
Host: QP6367 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Collagenase 3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6367.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Tyr104 - Cys471
Amino Acid Sequence: YNVFPRTLKW SKMNLTYRIV NYTPDMTHSE VEKAFKKAFK VWSDVTPLNF TRLHDGIADI MISFGIKEHG DFYPFDGPSG LLAHAFPPGP NYGGDAHFDD DETWTSSSKG YNLFLVAAHE FGHSLGLDHS KDPGALMFPI YTYTGKSHFM LPDDDVQGIQ SLYGPGDEDP NPKHPKTPDK CDPSLSLDAI TSLRGETMIF KDRFFWRLHP QQVDAELFLT KSFWPELPNR IDAAYEHPSH DLIFIFRGRK FWALNGYDIL EGYPKKISEL GLPKEVKKIS AAVHFEDTGK TLLFSGNQVW RYDDTNHIMD KDYPRLIEED FPGIGDKVDA VYEKNGYIYF FNGPIQFEYS IWSNRIVRVM PANSILWC
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Collagenase 3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Collagenase 3 Protein

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