SDS-PAGE separation of QP6525 followed by commassie total protein stain results in a primary band consistent with reported data for Perforin-1. These data demonstrate Greater than 80% as determined by SDS-PAGE.

Recombinant Human Perforin-1 Protein

$ 158.00 – $ 1,728.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP6525
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO, His
Host: E.coli, Yeast.
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 534

Product Number	Description	Price
QP6525-ec-10ug	Size: 10 ug, Tag: His-SUMO	$ 158.00
QP6525-ec-100ug	Size: 100 ug, Tag: His-SUMO	$ 398.00
QP6525-ec-1mg	Size: 1 mg, Tag: His-SUMO	$ 1,728.00

Shipping Information

2-4 weeks

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP6525-ec-10ug

Recombinant Human Perforin-1 Protein General Information
Alternate Names
HPLH2, PFN1, PFP, P1, FLH2
Curated Database and Bioinformatic Data
Gene Symbol	Prf1
Entrez Gene ID	5551
Ensemble Gene ID	ENSG00000180644
RefSeq Protein Accession(s)	NP_001076585.1
RefSeq mRNA Accession(s)	NM_001083116.1, NM_005041.4
UniProt ID(s)	P14222
UniGene ID(s)	Hs.2200
HGNC ID(s)	HGNC:9360
COSMIC ID Link(s)	Prf1
KEGG Gene ID(s)	hsa:5551
PharmGKB ID(s)	PA33732
General Description of Recombinant Human Perforin-1 Protein.
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune syst, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the mbrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

Human Perforin-1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Perforin-1 based upon sequence from Human

Host: QP6525 protein expressed in E.coli.

Tag: His-SUMO

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Perforin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.

Application Notes: Please contact us for application specific information for QP6525.

Bioactivity Data: Untested

Full Length? Full Length

Expression Region: Pro22 - Trp555

Amino Acid Sequence: PCHTAARSEC KRSHKFVPGA WLAGEGVDVT SLRRSGSFPV DTQRFLRPDG TCTLCENALQ EGTLQRLPLA LTNWRAQGSG CQRHVTRAKV SSTEAVARDA ARSIRNDWKV GLDVTPKPTS NVHVSVAGSH SQAANFAAQK THQDQYSFST DTVECRFYSF HVVHTPPLHP DFKRALGDLP HHFNASTQPA YLRLISNYGT HFIRAVELGG RISALTALRT CELALEGLTD NEVEDCLTVE AQVNIGIHGS ISAEAKACEE KKKKHKMTAS FHQTYRERHS EVVGGHHTSI NDLLFGIQAG PEQYSAWVNS LPGSPGLVDY TLEPLHVLLD SQDPRREALR RALSQYLTDR ARWRDCSRPC PPGRQKSPRD PCQCVCHGSA VTTQDCCPRQ RGLAQLEVTF IQAWGLWGDW FTATDAYVKL FFGGQELRTS TVWDNNNPIW SVRLDFGDVL LATGGPLRLQ VWDQDSGRDD DLLGTCDQAP KSGSHEVRCN LNHGHLKFRY HARCLPHLGG GTCLDYVPQM LLGEPPGNRS GAVW

Purity: Greater than 80% as determined by SDS-PAGE.

Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.

Concentration of Human Perforin-1 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol OR, if lyophilized, Tris-based buffer, 6% Trehalose

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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