SDS-PAGE separation of QP6540 followed by commassie total protein stain results in a primary band consistent with reported data for PSAP / Prosaposin. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human PSAP / Prosaposin Protein

$ 398.00 – $ 1,728.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP6540
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 81

Product Number	Description	Price
QP6540-ec-100ug	Size: 100 ug, Tag: GST	$ 398.00
QP6540-ec-1mg	Size: 1 mg, Tag: GST	$ 1,728.00

Shipping Information

2-4 weeks

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP6540-ec-10ug

Recombinant Human PSAP / Prosaposin Protein General Information
Alternate Names
PSAP, Prosaposin, SGP-1, AI037048
Curated Database and Bioinformatic Data
Gene Symbol	PSAP
Entrez Gene ID	5660
Ensemble Gene ID	ENSG00000197746
RefSeq Protein Accession(s)	NP_001035930.1
RefSeq mRNA Accession(s)	NM_001042465.2, NM_001042466.2, NM_002778.3
UniProt ID(s)	P07602
UniGene ID(s)	Hs.523004
HGNC ID(s)	HGNC:9498
COSMIC ID Link(s)	PSAP
KEGG Gene ID(s)	hsa:5660
PharmGKB ID(s)	PA33845
General Description of Recombinant Human PSAP / Prosaposin Protein.
Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate.Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases.Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12).Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.

Human PSAP / Prosaposin Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant PSAP / Prosaposin based upon sequence from Human

Host: QP6540 protein expressed in E. coli.

Tag: GST

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) PSAP / Prosaposin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.

Application Notes: Please contact us for application specific information for QP6540.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Ser311 - Thr391

Amino Acid Sequence: SDVYCEVCEF LVKEVTKLID NNKTEKEILD AFDKMCSKLP KSLSEECQEV VDTYGSSILS ILLEEVSPEL VCSMLHLCSG T

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.

Concentration of Human PSAP / Prosaposin Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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