SDS-PAGE separation of QP6778 followed by commassie total protein stain results in a primary band consistent with reported data for TGF-beta 1 / TGFB1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Bovine TGF-beta 1 / TGFB1 Protein

$ 728.00 – $ 2,468.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP6778
Species: Bovine
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 112

Product Number	Description	Price
QP6778-ec-100ug	Size: 100 ug, Tag: His	$ 728.00
QP6778-ec-1mg	Size: 1 mg, Tag: His	$ 2,468.00

Shipping Information

1-2 weeks

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP6778-ec-10ug

Recombinant Bovine TGF-beta 1 / TGFB1 Protein General Information
Curated Database and Bioinformatic Data
Gene Symbol	TGFB1
Entrez Gene ID	282089
RefSeq Protein Accession(s)	NP_001159540.1
RefSeq mRNA Accession(s)	NM_001166068.1
UniProt ID(s)	P18341
UniGene ID(s)	Bt.469
COSMIC ID Link(s)	TGFB1
KEGG Gene ID(s)	bta:282089
General Description of Recombinant Bovine TGF-beta 1 / TGFB1 Protein.
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone rodeling as it is a potent stimulator of osteoblastic bone formation, causing chotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.

Bovine TGF-beta 1 / TGFB1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant TGF-beta 1 / TGFB1 based upon sequence from Bovine

Host: QP6778 protein expressed in E. coli.

Tag: His

Protein Construction: A DNA sequence encoding the Bos taurus (Bovine) TGF-beta 1 / TGFB1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.

Application Notes: Please contact us for application specific information for QP6778.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Ala279 - Ser390

Amino Acid Sequence: ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.

Concentration of Bovine TGF-beta 1 / TGFB1 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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