SDS-PAGE separation of QP6780 followed by commassie total protein stain results in a primary band consistent with reported data for TGF-beta 1 / TGFB1. These data demonstrate Greater than 80% as determined by SDS-PAGE.

Recombinant Rat TGF-beta 1 / TGFB1 Protein

$ 578.00 – $ 2,468.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP6780
Species: Rat
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 249

Product Number	Description	Price
QP6780-ec-100ug	Size: 100 ug, Tag: His-SUMO	$ 578.00
QP6780-ec-1mg	Size: 1 mg, Tag: His-SUMO	$ 2,468.00

Shipping Information

2-4 weeks

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP6780-ec-10ug

Recombinant Rat TGF-beta 1 / TGFB1 Protein General Information
Alternate Names
TGF-beta 1, TGFB1, CED, TGFB, TGFbeta, LAP, DPD1
Curated Database and Bioinformatic Data
Gene Symbol	TGFB1
Entrez Gene ID	59086
Ensemble Gene ID	ENSRNOG00000020652
RefSeq Protein Accession(s)	NP_067589.1
RefSeq mRNA Accession(s)	NM_021578.2
UniProt ID(s)	P17246
UniGene ID(s)	Rn.40136
COSMIC ID Link(s)	TGFB1
KEGG Gene ID(s)	rno:59086
General Description of Recombinant Rat TGF-beta 1 / TGFB1 Protein.
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells

Rat TGF-beta 1 / TGFB1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant TGF-beta 1 / TGFB1 based upon sequence from Rat

Host: QP6780 protein expressed in E. coli.

Tag: His-SUMO

Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) TGF-beta 1 / TGFB1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.

Application Notes: Please contact us for application specific information for QP6780.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Leu30 - Arg278

Amino Acid Sequence: LSTCKTIDME LVKRKRIEAI RGQILSKLRL ASPPSQGEVP PGPLPEAVLA LYNSTRDRVA GESADPEPEP EADYYAKEVT RVLMVDRNNA IYDKTKDITH SIYMFFNTSD IREAVPEPPL LSRAELRLQR FKSTVEQHVE LYQKYSNNSW RYLGNRLLTP TDTPEWLSFD VTGVVRQWLN QGDGIQGFRF SAHCSCDSKD NVLHVEINGI SPKRRGDLGT IHDMNRPFLL LMATPLERAQ HLHSSRHRR

Purity: Greater than 80% as determined by SDS-PAGE.

Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.

Concentration of Rat TGF-beta 1 / TGFB1 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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