SEQUEST analysis of LC MS/MS spectra obtained from a run with QP6800 identified a match between this protein and the spectra of a peptide sequence that matches a region of TLR2 / CD282.
SEQUEST analysis of LC MS/MS spectra obtained from a run with QP6800 identified a match between this protein and the spectra of a peptide sequence that matches a region of TLR2 / CD282.Additional SEQUEST analysis of the LC MS/MS spectra from QP6800 identified an additional between this protein and the spectra of another peptide sequence that matches a region of TLR2 / CD282 confirming successful recombinant synthesis.

Recombinant Human TLR2 / CD282 Protein

$ 148.00$ 1,678.00
Please Select A Product To View The SKU.

SKU: QP6800
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 570

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Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP6800-ec-10ug
Recombinant Human TLR2 / CD282 Protein General Information
Alternate Names
TLR2, CD282, CD282, TIL4
Curated Database and Bioinformatic Data
Gene SymbolTLR2
Entrez Gene ID7097
Ensemble Gene IDENSG00000137462
RefSeq Protein Accession(s)NP_001305716.1
RefSeq mRNA Accession(s)NM_001318787.1, NM_001318789.1, NM_001318790.1, NM_001318791.1, NM_001318793.1, NM_001318795.1, NM_001318796.1, NM_003264.4, XM_011532215.2, XM_011532216.2, XM_017008573.1, XM_017008574.1, XM_017008575.1, XM_017008576.1
UniProt ID(s)O60603
UniGene ID(s)Hs.519033
HGNC ID(s)HGNC:11848
COSMIC ID Link(s)TLR2
KEGG Gene ID(s)hsa:7097
PharmGKB ID(s)PA36550
General Description of Recombinant Human TLR2 / CD282 Protein.
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Human TLR2 / CD282 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant TLR2 / CD282 based upon sequence from Human
Host: QP6800 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TLR2 / CD282, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6800.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Lys19 - Thr588
Amino Acid Sequence: KEESSNQASL SCDRNGICKG SSGSLNSIPS GLTEAVKSLD LSNNRITYIS NSDLQRCVNL QALVLTSNGI NTIEEDSFSS LGSLEHLDLS YNYLSNLSSS WFKPLSSLTF LNLLGNPYKT LGETSLFSHL TKLQILRVGN MDTFTKIQRK DFAGLTFLEE LEIDASDLQS YEPKSLKSIQ NVSHLILHMK QHILLLEIFV DVTSSVECLE LRDTDLDTFH FSELSTGETN SLIKKFTFRN VKITDESLFQ VMKLLNQISG LLELEFDDCT LNGVGNFRAS DNDRVIDPGK VETLTIRRLH IPRFYLFYDL STLYSLTERV KRITVENSKV FLVPCLLSQH LKSLEYLDLS ENLMVEEYLK NSACEDAWPS LQTLILRQNH LASLEKTGET LLTLKNLTNI DISKNSFHSM PETCQWPEKM KYLNLSSTRI HSVTGCIPKT LEILDVSNNN LNLFSLNLPQ LKELYISRNK LMTLPDASLL PMLLVLKISR NAITTFSKEQ LDSFHTLKTL EAGGNNFICS CEFLSFTQEQ QALAKVLIDW PANYLCDSPS HVRGQQVQDV RLSVSECHRT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human TLR2 / CD282 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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