SDS-PAGE separation of QP6865 followed by commassie total protein stain results in a primary band consistent with reported data for Ubiquitin-protein ligase E3A. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP6865 followed by commassie total protein stain results in a primary band consistent with reported data for Ubiquitin-protein ligase E3A. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Mouse Ubiquitin-protein ligase E3A Protein

$ 498.00$ 2,768.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6865
Species: Mouse
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: Flag, His
Host: E.coli, Yeast, Mammal.
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 329

Product NumberDescriptionPrice
QP6865-ma-20ug Size: 20 ug, Tag: FLAG $ 438.00
QP6865-ma-100ug Size: 100 ug, Tag: FLAG $ 1,228.00
QP6865-ye-100ug Size: 100 ug, Tag: His $ 688.00
QP6865-ye-500ug Size: 500 ug, Tag: His $ 1,918.00
QP6865-ec-100ug Size: 100 ug, Tag: His $ 728.00
QP6865-ec-1mg Size: 1 mg, Tag: His $ 2,468.00
Shipping Information
3-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP6865-ma-20ug
Recombinant Mouse Ubiquitin-protein ligase E3A Protein General Information
Alternate Names
A130086L21Rik, mKIAA4216, 4732496B02, 5830462N02Rik, Hpve6a
Curated Database and Bioinformatic Data
Gene SymbolUbe3a
Entrez Gene ID22215
Ensemble Gene IDENSMUSG00000025326
RefSeq Protein Accession(s)NP_035798.2
RefSeq mRNA Accession(s)NM_011668.2, NM_173010.3, XM_006540799.3, XM_011250847.2, XM_017322125.1
UniProt ID(s)O08759
UniGene ID(s)Mm.9002
COSMIC ID Link(s)Ube3a
KEGG Gene ID(s)mmu:22215
General Description of Recombinant Mouse Ubiquitin-protein ligase E3A Protein.
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Additionally, may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. Finally, UBE3A also promotes its own degradation in vivo (By similarity). Plays an important role in the regulation of the circadian clock: involved in the ubiquitination of the core clock component ARNTL/BMAL1, leading to its proteasomal degradation (PubMed:24728990)

Mouse Ubiquitin-protein ligase E3A Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Ubiquitin-protein ligase E3A based upon sequence from Mouse
Host: QP6865 protein expressed in E.coli, Yeast, Mammal..
Tag: Flag
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Ubiquitin-protein ligase E3A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6865.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: His542 - Val870
Amino Acid Sequence: HIIDDALVRL EMIAMENPAD LKKQLYVEFE GEQGVDEGGV SKEFFQLVVE EIFNPDIGMF TYDEATKLFW FNPSSFETEG QFTLIGILGL AIYNNCILDV HFPMVVYRKL MGKKGTFRDL GDSHPVLYQS LKDLLEYEGS VEDDMMITFQ ISQTDLFGNP MMYDLKENGD KIPITNENRK EFVISYSDYI LNKSVEKQFK AFRRGFHMVT NESPLKYLFR PEEIELLICG SRNLDFQALE ETTEYDGGYT RESVVIREFW EIVHSFTDEQ KRLFLLFTTG TDRAPVGGLG KLKMIIAKNG PDTERLPTSH TCFNVLLLPE YSSKEKLNV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Ubiquitin-protein ligase E3A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Mouse Ubiquitin-protein ligase E3A Protein

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