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Recombinant Human UCHL5 Protein

$ 148.00$ 1,678.00
Please Select A Product To View The SKU.

SKU: QP6866
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 326

Size
Tag Clear selection
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP6866-ec-10ug
Recombinant Human UCHL5 Protein General Information
Alternate Names
UCH-L5, CGI-70, UCH37, INO80R, Ubiquitin carboxyl-terminal hydrolase isozyme
Molecular Weight
Isoform 4
Curated Database and Bioinformatic Data
Gene SymbolUCHL5
Entrez Gene ID51377
Ensemble Gene IDENSG00000116750
RefSeq Protein Accession(s)NP_001186190.1
RefSeq mRNA Accession(s)NM_001199261.1, NM_001199262.1, NM_001199263.1, NM_015984.3
UniProt ID(s)Q9Y5K5
UniGene ID(s)Hs.145469
HGNC ID(s)HGNC:19678
COSMIC ID Link(s)UCHL5
KEGG Gene ID(s)hsa:51377
PharmGKB ID(s)PA134916228
General Description of Recombinant Human UCHL5 Protein.
Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.

Human UCHL5 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant UCHL5 based upon sequence from Human
Isoform: Isoform 4
Host: QP6866 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) UCHL5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6866.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 4
Expression Region: Met1 - Lys326
Amino Acid Sequence: MTGNAGEWCL MESDPGVFTE LIKGFGCRGA QVEEIWSLEP ENFEKLKPVH GLIFLFKWQP GEEPAGSVVQ DSRLDTIFFA KQVINNACAT QAIVSVLLNC THQDVHLGET LSEFKEFSQS FDAAMKGLAL SNSDVIRQVH NSFARQQMFE FDTKTSAKEE DAFHFVSYVP VNGRLYELDG LREGPIDLGA CNQDDWISAV RPVIEKRIQK YSEGEIRFNL MAIVSDRKMI YEQKIAELQR QLAEEPMDTD QGNSMLSAIQ SEVAKNQMLI EEEVQKLKRY KIENIRRKHN YLPFIMELLK TLAEHQQLIP LVEKFEKHFE KTLLGK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human UCHL5 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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