SDS-PAGE separation of QP6998 followed by commassie total protein stain results in a primary band consistent with reported data for Complement C4-B. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP6998 followed by commassie total protein stain results in a primary band consistent with reported data for Complement C4-B. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Complement C4-B Protein

$ 168.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6998
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO, His
Host: E.coli, Yeast.
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 291

Product NumberDescriptionPrice
QP6998-ec-10ug Size: 10 ug, Tag: His-SUMO $ 148.00
QP6998-ec-50ug Size: 50 ug, Tag: His-SUMO $ 398.00
QP6998-ec-500ug Size: 500 ug, Tag: His-SUMO $ 1,728.00
QP6998-ye-50ug Size: 50 ug, Tag: His $ 468.00
QP6998-ye-200ug Size: 200 ug, Tag: His $ 1,298.00
Shipping Information
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP6998-ec-50ug
Recombinant Human Complement C4-B Protein General Information
Alternate Names
C4B12, C4B3, C4B1, C4F, C4BD, CO4, C4B2, CPAMD3, C4B5, C4B_2, CH
Curated Database and Bioinformatic Data
Gene SymbolC4B
Entrez Gene ID100293534
Ensemble Gene IDENSG00000228454
RefSeq Protein Accession(s)NP_001002029.3
RefSeq mRNA Accession(s)NM_001002029.3, NM_001242823.2
UniProt ID(s)P0C0L5
UniGene ID(s)Hs.534847
HGNC ID(s)HGNC:1324
COSMIC ID Link(s)C4B
KEGG Gene ID(s)hsa:100293534
PharmGKB ID(s)PA25904
General Description of Recombinant Human Complement C4-B Protein.
Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complent pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.Derived from proteolytic degradation of complent C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Human Complement C4-B Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Complement C4-B based upon sequence from: Human
Host: QP6998 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Complement C4-B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6998.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu1454 - Val1744
Amino Acid Sequence: EAPKVVEEQE SRVHYTVCIW RNGKVGLSGM AIADVTLLSG FHALRADLEK LTSLSDRYVS HFETEGPHVL LYFDSVPTSR ECVGFEAVQE VPVGLVQPAS ATLYDYYNPE RRCSVFYGAP SKSRLLATLC SAEVCQCAEG KCPRQRRALE RGLQDEDGYR MKFACYYPRV EYGFQVKVLR EDSRAAFRLF ETKITQVLHF TKDVKAAANQ MRNFLVRASC RLRLEPGKEY LIMGLDGATY DLEGHPQYLL DSNSWIEEMP SERLCRSTRQ RAACAQLNDF LQEYGTQGCQ V
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Complement C4-B Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Complement C4-B Protein

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