SDS-PAGE separation of QP8080 followed by commassie total protein stain results in a primary band consistent with reported data for IL1F5 / IL36RN. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human IL1F5 / IL36RN Protein

$ 398.00 – $ 1,728.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP8080
Species: Human
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 155

Product Number	Description	Price
QP8080-ec-100ug	Size: 100 ug, Tag: His-SUMO	$ 398.00
QP8080-ec-1mg	Size: 1 mg, Tag: His-SUMO	$ 1,728.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP8080-ec-10ug

Recombinant Human IL1F5 / IL36RN Protein General Information
Alternate Names
IL1F5; IL36RN; IL1HY1; FIL1(DELTA); PSORP; IL1RP3; IL1L1; IL36RA; FIL1; IL-36Ra; PSORS14; FIL1D; IL1F5
Curated Database and Bioinformatic Data
Gene Symbol	IL36RN
Entrez Gene ID	26525
Ensemble Gene ID	ENSG00000136695
RefSeq Protein Accession(s)	NP_036407.1
RefSeq mRNA Accession(s)	NM_012275.2, NM_173170.1
UniProt ID(s)	Q9UBH0
UniGene ID(s)	Hs.516301
HGNC ID(s)	HGNC:15561
COSMIC ID Link(s)	IL36RN
KEGG Gene ID(s)	hsa:26525
PharmGKB ID(s)	PA38388
General Description of Recombinant Human IL1F5 / IL36RN Protein.
Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling syst that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 syst with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Human IL1F5 / IL36RN Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant IL1F5 / IL36RN based upon sequence from: Human

Host: QP8080 protein expressed in E. coli.

Tag: His-SUMO

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IL1F5 / IL36RN, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP8080.

Bioactivity Data: Untested

Full Length? Full Length

Expression Region: Met1 - Asp155

Amino Acid Sequence: MVLSGALCFR MKDSALKVLY LHNNQLLAGG LHAGKVIKGE EISVVPNRWL DASLSPVILG VQGGSQCLSC GVGQEPTLTL EPVNIMELYL GAKESKSFTF YRRDMGLTSS FESAAYPGWF LCTVPEADQP VRLTQLPENG GWNAPITDFY FQQCD

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human IL1F5 / IL36RN Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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