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Recombinant Human Protein C8orf4 Protein

$ 578.00 – $ 2,468.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8178
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 106

Product NumberDescriptionPrice
QP8178-ec-100ug Size: 100 ug, Tag: GST $ 578.00
QP8178-ec-1mg Size: 1 mg, Tag: GST $ 2,468.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8178-ec-10ug
Recombinant Human Protein C8orf4 Protein General Information
Alternate Names
TC-1; TC1
Curated Database and Bioinformatic Data
Gene SymbolC8orf4
Entrez Gene ID56892
Ensemble Gene IDENSG00000176907
RefSeq Protein Accession(s)NP_064515.1
RefSeq mRNA Accession(s)NM_020130.4
UniProt ID(s)Q9NR00
UniGene ID(s)Hs.591849
HGNC ID(s)HGNC:1357
COSMIC ID Link(s)C8orf4
KEGG Gene ID(s)hsa:56892
PharmGKB ID(s)PA25962
General Description of Recombinant Human Protein C8orf4 Protein.
Seems to be involved in the regulation of cell growth an differentiation, may play different and opposite roles depending on the tissue or cell type. May enhance the WNT-CTNNB1 pathway by relieving antagonistic activity of CBY1. Enhances the proliferation of follicular dendritic cells. Plays a role in the mitogen-activated MAPK2/3 signaling pathway, positively regulates G1-to-S-phase transition of the cell cycle. In endothelial cells, enhances key inflammatory mediators and inflammatory response through the modulation of NF-kappaB transcriptional regulatory activity. Involved in the regulation of heat shock response, seems to play a positive feedback with HSF1 to modulate heat-shock downstream gene expression. Plays a role in the regulation of hematopoiesis even if the mechanisms are unknown. In cancers such as thyroid or lung cancer, it has been described as promoter of cell proliferation, G1-to-S-phase transition and inhibitor of apoptosis. However, it negatively regulates self-renewal of liver cancer cells via suppresion of NOTCH2 signaling.

Human Protein C8orf4 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Protein C8orf4 based upon sequence from: Human
Host: QP8178 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Protein C8orf4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8178.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - His106
Amino Acid Sequence: MKAKRSHQAV IMSTSLRVSP SIHGYHFDTA SRKKAVGNIF ENTDQESLER LFRNSGDKKA EERAKIIFAI DQDVEEKTRA LMALKKRTKD KLFQFLKLRK YSIKVH
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Protein C8orf4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Protein C8orf4 Protein