SDS-PAGE separation of QP9080 followed by commassie total protein stain results in a primary band consistent with reported data for Corticotropin-releasing factor receptor 1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Corticotropin-releasing factor receptor 1 Protein

$ 468.00 – $ 2,008.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP9080
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 99

Product Number	Description	Price
QP9080-ye-100ug	Size: 100 ug, Tag: His	$ 468.00
QP9080-ye-1mg	Size: 1 mg, Tag: His	$ 2,008.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP9080-ye-10ug

Recombinant Human Corticotropin-releasing factor receptor 1 Protein General Information
Alternate Names
MGC57346-CRHR1; CRF1; CRHR1L; CRF-R-1; CRF-R1; CRF-R; CRHR; CRH-R1; CRFR-1; CRFR1; CRH-R-1
Curated Database and Bioinformatic Data
Gene Symbol	CRHR1
Entrez Gene ID	104909134
Ensemble Gene ID	ENSG00000120088
RefSeq Protein Accession(s)	NP_001138618.1
RefSeq mRNA Accession(s)	NM_001145146.1, NM_001145147.1, NM_001145148.1, NM_001256299.2, NM_001303016.1, NM_001303018.1, NM_004382.4
UniProt ID(s)	P34998
UniGene ID(s)	Hs.417628
HGNC ID(s)	HGNC:2357
COSMIC ID Link(s)	CRHR1
KEGG Gene ID(s)	hsa:104909134
PharmGKB ID(s)	PA26874
General Description of Recombinant Human Corticotropin-releasing factor receptor 1 Protein.
G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal bryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.

Human Corticotropin-releasing factor receptor 1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Corticotropin-releasing factor receptor 1 based upon sequence from: Human

Host: QP9080 protein expressed in Yeast.

Tag: His

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Corticotropin-releasing factor receptor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP9080.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Ala23 - Ile121

Amino Acid Sequence: ASLQDQHCES LSLASNISGL QCNASVDLIG TCWPRSPAGQ LVVRPCPAFF YGVRYNTTNN GYRECLANGS WAARVNYSEC QEILNEEKKS KVHYHVAVI

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human Corticotropin-releasing factor receptor 1 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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