SDS-PAGE separation of QP9185 followed by commassie total protein stain results in a primary band consistent with reported data for HSD11B2. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human HSD11B2 Protein

$ 528.00$ 1,458.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9185
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 405

Product NumberDescriptionPrice
QP9185-ye-100ug Size: 100 ug, Tag: His $ 528.00
QP9185-ye-500ug Size: 500 ug, Tag: His $ 1,458.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9185-ye-10ug
Recombinant Human HSD11B2 Protein General Information
Alternate Names
SDR9C3; HSD11K; HSD2; AME1; AME; Corticosteroid 11-beta-dehydrogenase isozyme
Curated Database and Bioinformatic Data
Gene SymbolHSD11B2
Entrez Gene ID3291
Ensemble Gene IDENSG00000176387
RefSeq Protein Accession(s)NP_000187.3
RefSeq mRNA Accession(s)NM_000196.3
UniProt ID(s)P80365
UniGene ID(s)Hs.1376
HGNC ID(s)HGNC:5209
COSMIC ID Link(s)HSD11B2
KEGG Gene ID(s)hsa:3291
PharmGKB ID(s)PA29477
General Description of Recombinant Human HSD11B2 Protein.
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

Human HSD11B2 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant HSD11B2 based upon sequence from: Human
Host: QP9185 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) HSD11B2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9185.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - Arg405
Amino Acid Sequence: MERWPWPSGG AWLLVAARAL LQLLRSDLRL GRPLLAALAL LAALDWLCQR LLPPPAALAV LAAAGWIALS RLARPQRLPV ATRAVLITGC DSGFGKETAK KLDSMGFTVL ATVLELNSPG AIELRTCCSP RLRLLQMDLT KPGDISRVLE FTKAHTTSTG LWGLVNNAGH NEVVADAELS PVATFRSCME VNFFGALELT KGLLPLLRSS RGRIVTVGSP AGDMPYPCLG AYGTSKAAVA LLMDTFSCEL LPWGVKVSII QPGCFKTESV RNVGQWEKRK QLLLANLPQE LLQAYGKDYI EHLHGQFLHS LRLAMSDLTP VVDAITDALL AARPRRRYYP GQGLGLMYFI HYYLPEGLRR RFLQAFFISH CLPRALQPGQ PGTTPPQDAA QDPNLSPGPS PAVAR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human HSD11B2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human HSD11B2 Protein