SDS-PAGE separation of QP9348 followed by commassie total protein stain results in a primary band consistent with reported data for CD133 / PROM1 / Prominin 1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

DISCONTINUED: Recombinant Human CD133 / PROM1 / Prominin 1 Protein

Please Select Product Options Below To View The Catalog Number.

SKU: QP9348
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 285

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Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP9348-ye-10ug

Recombinant Human CD133 / PROM1 / Prominin 1 Protein General Information
Alternate Names
CD133; PROM1; Prominin 1; Prom; CD133
Curated Database and Bioinformatic Data
Gene Symbol	PROM1
Entrez Gene ID	8842
Ensemble Gene ID	ENSG00000007062
RefSeq Protein Accession(s)	NP_001139319.1
RefSeq mRNA Accession(s)	NM_001145847.1, NM_001145848.1, NM_001145849.1, NM_001145850.1, NM_001145851.1, NM_001145852.1, NM_006017.2, XM_005248195.4, XM_005248196.4, XM_011513890.1, XM_011513892.2, XM_011513893.2, XM_011513894.2, XM_011513895.2, XM_011513896.2, XM_011513897.2, XM_011513899.2, XM_011513900.2, XM_011513902.2, XM_017008799.1, XM_017008802.1, XM_017008803.1, XM_017008804.1, XM_017008805.1
UniProt ID(s)	O43490
UniGene ID(s)	Hs.614734
HGNC ID(s)	HGNC:9454
COSMIC ID Link(s)	PROM1
KEGG Gene ID(s)	hsa:8842
PharmGKB ID(s)	PA33807
General Description of Recombinant Human CD133 / PROM1 / Prominin 1 Protein.
May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma mbrane microdomains and may play a role in the organization of the apical plasma mbrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner .

PRODUCT DISCONTINUED

Human CD133 / PROM1 / Prominin 1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant CD133 / PROM1 / Prominin 1 based upon sequence from: Human

Host: QP9348 protein expressed in Yeast.

Tag: His

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CD133 / PROM1 / Prominin 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP9348.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Gly508 - Asn792

Amino Acid Sequence: GANVEKLICE PYTSKELFRV LDTPYLLNED WEYYLSGKLF NKSKMKLTFE QVYSDCKKNR GTYGTLHLQN SFNISEHLNI NEHTGSISSE LESLKVNLNI FLLGAAGRKN LQDFAACGID RMNYDSYLAQ TGKSPAGVNL LSFAYDLEAK ANSLPPGNLR NSLKRDAQTI KTIHQQRVLP IEQSLSTLYQ SVKILQRTGN GLLERVTRIL ASLDFAQNFI TNNTSSVIIE ETKKYGRTII GYFEHYLQWI EFSISEKVAS CKPVATALDT AVDVFLCSYI IDPLN

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human CD133 / PROM1 / Prominin 1 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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