SDS-PAGE separation of QP9719 followed by commassie total protein stain results in a primary band consistent with reported data for Fusion glycoprotein F0. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Fusion glycoprotein F0

$ 468.00 – $ 1,298.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP9719
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 438

Product Number	Description	Price
QP9719-ye-100ug	Size: 100 ug, Tag: His	$ 468.00
QP9719-ye-500ug	Size: 500 ug, Tag: His	$ 1,298.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP9719-ye-10ug

Recombinant Human Fusion glycoprotein F0 Protein (137-574aa) General Information
Alternate Names
HRSVgp08
Curated Database and Bioinformatic Data
Gene Symbol	F
Entrez Gene ID	1489825
RefSeq Protein Accession(s)	NP_056863.1
RefSeq mRNA Accession(s)	NC_001781.1
UniProt ID(s)	O36634
KEGG Gene ID(s)	vg:1489825
General Description of Recombinant Human Fusion glycoprotein F0 Protein (137-574aa).
During virus entry, induces fusion of viral and cellular mbranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2. Interacts directly with heparan sulfate and may participates in virus attachment. Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity. Later in infection, proteins F expressed at the plasma mbrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigger p53-dependent apoptosis.

Human Fusion glycoprotein F0 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Fusion glycoprotein F0 based upon sequence from: Human

Host: QP9719 protein expressed in Yeast.

Tag: His

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Fusion glycoprotein F0, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP9719.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Phe137 - Lys574

Amino Acid Sequence: FLGFLLGVGS AIASGIAVSK VLHLEGEVNK IKNALLSTNK AVVSLSNGVS VLTSKVLDLK NYINNQLLPI VNQQSCRISN IETVIEFQQK NSRLLEINRE FSVNAGVTTP LSTYMLTNSE LLSLINDMPI TNDQKKLMSS NVQIVRQQSY SIMSIIKEEV LAYVVQLPIY GVIDTPCWKL HTSPLCTTNI KEGSNICLTR TDRGWYCDNA GSVSFFPQAD TCKVQSNRVF CDTMNSLTLP SEVSLCNTDI FNSKYDCKIM TSKTDISSSV ITSLGAIVSC YGKTKCTASN KNRGIIKTFS NGCDYVSNKG VDTVSVGNTL YYVNKLEGKN LYVKGEPIIN YYDPLVFPSD EFDASISQVN EKINQSLAFI RRSDELLHNV NTGKSTTNIM ITTIIIVIIV VLLSLIAIGL LLYCKAKNTP VTLSKDQLSG INNIAFSK

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human Fusion glycoprotein F0 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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