SDS-PAGE separation of QP9919 followed by commassie total protein stain results in a primary band consistent with reported data for Ripk3. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Mouse Ripk3 Protein

$ 578.00 – $ 1,588.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP9919
Species: Mouse
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 486

Product Number	Description	Price
QP9919-ye-100ug	Size: 100 ug, Tag: His	$ 578.00
QP9919-ye-500ug	Size: 500 ug, Tag: His	$ 1,588.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP9919-ye-10ug

Recombinant Mouse Ripk3 Protein General Information
Alternate Names
Rip3; 2610528K09Rik; AW107945; Receptor-interacting serine/threonine-protein kinase
Curated Database and Bioinformatic Data
Gene Symbol	Ripk3
Entrez Gene ID	56532
Ensemble Gene ID	ENSMUSG00000022221
RefSeq Protein Accession(s)	NP_064339.2
RefSeq mRNA Accession(s)	NM_019955.2
UniProt ID(s)	Q9QZL0
UniGene ID(s)	Mm.46612
COSMIC ID Link(s)	Ripk3
KEGG Gene ID(s)	mmu:56532
General Description of Recombinant Mouse Ripk3 Protein.
Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family mbers. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

Mouse Ripk3 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Ripk3 based upon sequence from Mouse

Host: QP9919 protein expressed in Yeast.

Tag: His

Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Ripk3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.

Application Notes: Please contact us for application specific information for QP9919.

Bioactivity Data: Untested

Full Length? Full Length

Expression Region: Met1 - Lys486

Amino Acid Sequence: MSSVKLWPTG ASAVPLVSRE ELKKLEFVGK GGFGVVFRAH HRTWNHDVAV KIVNSKKISW EVKAMVNLRN ENVLLLLGVT EDLQWDFVSG QALVTRFMEN GSLAGLLQPE CPRPWPLLCR LLQEVVLGMC YLHSLDPPLL HRDLKPSNIL LDPELHAKLA DFGLSTFQGG SQSGSGSGSG SRDSGGTLAY LDPELLFKVN LKASKASDVY SFGILVWAVL AGREAELVDK TSLIRETVCD RQSRPPLTEL PPGSPETPGL EKLKELMIHC WGSQSENRPS FQDCEPKTNE VYNLVKDKVD AAVSEVKHYL SQHRSSGRNL SAREPSQRGT EMDCPRETMV SKMLDRLHLE EPSGPVPGKC PERQAQDTSV GPATPARTSS DPVAGTPQIP HTLPFRGTTP GPVFTETPGP HPQRNQGDGR HGTPWYPWTP PNPMTGPPAL VFNNCSEVQI GNYNSLVAPP RTTASSSAKY DQAQFGRGRG WQPFHK

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.

Concentration of Mouse Ripk3 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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