Recombinant Human TNF-alpha Protein

$ 78.00$ 1,458.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP1385
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 158

Product NumberDescriptionPrice
QP1385-10 ug Size: 10 ug, Tag: Untagged (Native Protein) $ 69.00
QP1385-50 ug Size: 50 ug, Tag: Untagged (Native Protein) $ 169.00
QP1385-500 ug Size: 500 ug, Tag: Untagged (Native Protein) $ 759.00
QP1385-1 mg Size: 1 mg, Tag: Untagged (Native Protein) $ 1,298.00
Shipping Information
1-2 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP1385-10 ug
Recombinant Human TNF-alpha Protein General Information
Alternate Names
TNF-alpha, Tnfa, Tnfsf1a, Tnlg1f, TNF-a, DIF, TNF-alpha, TNFalpha, TNFSF2
Curated Database and Bioinformatic Data
Gene Symbol TNF
Entrez Gene ID 7124
Ensemble Gene ID ENSG00000204490
RefSeq Protein Accession(s) NP_000585.2
RefSeq mRNA Accession(s) NM_000594.3
UniProt ID(s) P01375
UniGene ID(s) Hs.241570
HGNC ID(s) HGNC:11892
COSMIC ID Link(s) TNF
KEGG Gene ID(s) hsa:7124
PharmGKB ID(s) PA435
General Description of Recombinant Human TNF-alpha Protein.
Tumor necrosis factor alpha (TNFa) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNFa signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNFa functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.

Human TNF-alpha Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant TNF-alpha based upon sequence from Human
Host: QP1385 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1385.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 2 ng/mL in the Cytolysis of mouse L929 cells in the presence of Actinomycin D assay. The bioactivity acceptance criteria is set at 5 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIAL
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human TNF-alpha Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human TNF-alpha Protein