SEQUEST analysis of LC MS/MS spectra obtained from a run with QP9276 identified a match between this protein and the spectra of a peptide sequence that matches a region of CD10 / Neprilysin / MME.

Additional SEQUEST analysis of the LC MS/MS spectra from QP9276 identified an additional between this protein and the spectra of another peptide sequence that matches a region of CD10 / Neprilysin / MME confirming successful recombinant synthesis.

Recombinant Human CD10 / Neprilysin / MME Protein

$ 468.00 – $ 1,298.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP9276
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 699

Product Number	Description	Price
QP9276-ye-100ug	Size: 100 ug, Tag: His	$ 468.00
QP9276-ye-500ug	Size: 500 ug, Tag: His	$ 1,298.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP9276-ye-10ug

Recombinant Human CD10 / Neprilysin / MME Protein General Information
Alternate Names
CD10; Neprilysin; MME; C85356; SFE; NEP; CD10; 6030454K05Rik; CALLA
Curated Database and Bioinformatic Data
Gene Symbol	MME
Entrez Gene ID	4311
Ensemble Gene ID	ENSG00000196549
RefSeq Protein Accession(s)	NP_000893.2
RefSeq mRNA Accession(s)	NM_000902.3, NM_007287.2, NM_007288.2, NM_007289.2, XM_006713646.3, XM_006713647.3, XM_011512855.2, XM_011512856.2, XM_011512857.2
UniProt ID(s)	P08473
UniGene ID(s)	Hs.307734
HGNC ID(s)	HGNC:7154
COSMIC ID Link(s)	MME
KEGG Gene ID(s)	hsa:4311
PharmGKB ID(s)	PA30864
General Description of Recombinant Human CD10 / Neprilysin / MME Protein.
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids . Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond . Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 . Involved in the degradation of atrial natriuretic factor (ANF) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers .

Human CD10 / Neprilysin / MME Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant CD10 / Neprilysin / MME based upon sequence from: Human

Host: QP9276 protein expressed in Yeast.

Tag: His

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CD10 / Neprilysin / MME, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP9276.

Bioactivity Data: Untested

Full Length? Extracellular Domain

Expression Region: Tyr52 - Trp750

Amino Acid Sequence: YDDGICKSSD CIKSAARLIQ NMDATTEPCT DFFKYACGGW LKRNVIPETS SRYGNFDILR DELEVVLKDV LQEPKTEDIV AVQKAKALYR SCINESAIDS RGGEPLLKLL PDIYGWPVAT ENWEQKYGAS WTAEKAIAQL NSKYGKKVLI NLFVGTDDKN SVNHVIHIDQ PRLGLPSRDY YECTGIYKEA CTAYVDFMIS VARLIRQEER LPIDENQLAL EMNKVMELEK EIANATAKPE DRNDPMLLYN KMTLAQIQNN FSLEINGKPF SWLNFTNEIM STVNISITNE EDVVVYAPEY LTKLKPILTK YSARDLQNLM SWRFIMDLVS SLSRTYKESR NAFRKALYGT TSETATWRRC ANYVNGNMEN AVGRLYVEAA FAGESKHVVE DLIAQIREVF IQTLDDLTWM DAETKKRAEE KALAIKERIG YPDDIVSNDN KLNNEYLELN YKEDEYFENI IQNLKFSQSK QLKKLREKVD KDEWISGAAV VNAFYSSGRN QIVFPAGILQ PPFFSAQQSN SLNYGGIGMV IGHEITHGFD DNGRNFNKDG DLVDWWTQQS ASNFKEQSQC MVYQYGNFSW DLAGGQHLNG INTLGENIAD NGGLGQAYRA YQNYIKKNGE EKLLPGLDLN HKQLFFLNFA QVWCGTYRPE YAVNSIKTDV HSPGNFRIIG TLQNSAEFSE AFHCRKNSYM NPEKKCRVW

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human CD10 / Neprilysin / MME Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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