PDF DatasheetHuman Anti-Blood Group Antigen H Type 2 Antibody Product Attributes
Species: Human
Tested Applications: Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Immunofluorescence (0.5-1ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1.0ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-Blood Group Antigen H Type 2 Antibody Clone: 19-OLE
Clone 19-OLE Host and Isotype: Mouse IgM kappa
Anti-Human Blood Group Antigen H Type 2 Positive Control Sample: KG1 cells or human colorectal carcinoma.
Cellular Localization of Antibody <19-OLE Staining: Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Mucinous colonic adenocarcinoma
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
Blood Group Antigen H Type 2 Previously Observed Antibody Staining Patterns
| Blood Group Antigen H Type 2 General Information | |
|---|---|
| Alternate Names | |
| Histo-blood group ABO system transferase, ABO | |
| Molecular Weight | |
| Multiple | |
| Chromosomal Location | |
| 9q34.2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ABO |
| Entrez Gene ID | 28 |
| Ensemble Gene ID | ENSG00000281879, ENSG00000175164 |
| RefSeq Protein Accession(s) | NP_065202 |
| RefSeq mRNA Accession(s) | NM_020469 |
| RefSeq Genomic Accession(s) | NW_009646201, NG_006669, NC_018920, NC_000009 |
| UniProt ID(s) | A0A089QDC1, P16442 |
| UniGene ID(s) | A0A089QDC1, P16442 |
| HGNC ID(s) | 79 |
| Cosmic ID(s) | ABO |
| KEGG Gene ID(s) | hsa:28 |
| PharmGKB ID(s) | PA24415 |
| General Description of Blood Group Antigen H Type 2. | |
| Recognizes the blood group H type 2 antigens, trisaccharide Fuc 1-2Gal 1-4GlcNAc 1 of human origin. This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B,, H. A, B,, AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells, granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas,, colon carcinomas. | |
Limitations and Warranty
enQuire Bio’s Blood Group Antigen H Type 2 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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