Antibody (Suitable for clinical applications)
Specification | Recommendation |
---|---|
Recommended Dilution (Conc) | 1:25-1:50 |
Pretreatment | Enzymatic Antigen Retrieval (eg. Histozyme) |
Incubation Parameters | 30 min at Room Temperature |
Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.
Cadherin, Pan Information for Pathologists
Summary:
Definition / general See also E-cadherin, N-cadherin. Molecules that establish links between adjacent cells by forming zipper like structures at adherens junctions. Linked to cytoskeleton via catenins (cadherin to beta catenin, beta catenin to alpha catenin, alpha catenin to actin) to stabilize adherens junction. Homophilic interactions (like-like) causes clustering of embryonic cells with others from same tissue.
Cadherin, Pan General Information | |
---|---|
Alternate Names | |
Curated Database and Bioinformatic Data | |
UniProt ID(s) | Multiple |
General Description of Cadherin, Pan . | |
This antibody reacts with pan cadherin with a distinct 135 kDa band from a wide variety of tissues. Cadherins are members of a multigene family of single chain glycoprotein receptors mediating Ca2+ dependent cell-cell adhesion. |
There are no reviews yet.