PDF DatasheetAntibody (Suitable for clinical applications)
Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
| Specification | Recommendation |
|---|---|
| Recommended Dilution (Conc) | 1:50-1:100 |
| Pretreatment | EDTA Buffer pH 8.0 |
| Incubation Parameters | 30 min at Room Temperature |
Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.
Clonality: Monoclonal
Anti-CD68, Macrophage Antibody Clone: KP1
Host and Isotype: Mouse IgG1, kappa
Recommended Positive Control Sample: Tonsil
Cellular Localization of Antibody KP1 Staining: Cell membrane
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: Subcellular fraction of human alveolar macrophages.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.
CD68, Macrophage Information for Pathologists
| CD68, Macrophage General Information | |
|---|---|
| Alternate Names | |
| Molecular Weight | |
| 37.4 kDa | |
| Chromosomal Location | |
| p13.1 [chr: 17] [chr_start: 7579491] [chr_end: 7582111] [strand: 1] | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CD68 |
| Entrez Gene ID | 968 |
| RefSeq Protein Accession(s) | NP_001035148; NP_001242 |
| RefSeq mRNA Accession(s) | NM_001040059; NM_001251 |
| RefSeq Genomic Accession(s) | NC_000017; NG_009204 |
| UniProt ID(s) | P34810 |
| PharmGKB ID(s) | PA26232 |
| KEGG Gene ID(s) | hsa:968 |
| General Description of CD68, Macrophage . | |
| This antibody is specific to macrophages in a wide variety of human tissues. It reacts with myeloid precursors and peripheral blood granulocytes. It also stains a cell population known as plasmacytoid T cells. | |
Limitations and Warranty
This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.
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