![Analysis of Mass Spec data (dashed-line) of fractions stained with Ep-CAM / CD326 MS-QAVA™ monoclonal antibody [Clone: EGP40/1372] (solid-line), reveals that less than 5.2% of signal is attributable to non-specific binding of anti-Ep-CAM / CD326 [Clone: EGP40/1372] to targets other than TACSTD1 protein. Even frequently cited antibodies have much greater non-specific interactions, averaging over 30%. Data in image is from analysis in A431, RT4 and MCF7 cells.](https://cdn-enquirebio.pressidium.com/wp-content/uploads/2017/10/enQuire-Bio-4072-MSM12-P0-anti-EpCAM-CD326-antibody.png "EpCAM / CD326 Antibody Mass Spec Validation Data")
PDF DatasheetHuman Anti-EpCAM / CD326 Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC). Additionally, this antibody has been validated by MS-QAVA™. Specificity has been quantitatively determined via Mass Spec.
Clonality: Monoclonal
Anti-EpCAM / CD326 Antibody Clone: EGP40/1372
Clone EGP40/1372 Host and Isotype: Mouse IgG1
Anti-Human EpCAM / CD326 Positive Control Sample: HT29 cells or Ovarian carcinoma
Cellular Localization of Antibody Cell surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human EpCAM protein fragment from the extracellular domain (aa77-202)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
EpCAM / CD326 Previously Observed Antibody Staining Patterns
| EpCAM / CD326 General Information | |
|---|---|
| Alternate Names | |
| EpCAM, Epithelial cell adhesion molecule, EGP40, CD326, Cluster of Differentiation 326 | |
| Molecular Weight | |
| 40-43kDa | |
| Chromosomal Location | |
| 2p21 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TACSTD1 |
| Entrez Gene ID | 4072 |
| Ensemble Gene ID | ENSG00000119888 |
| RefSeq Protein Accession(s) | NP_002345 |
| RefSeq mRNA Accession(s) | NM_002354, |
| RefSeq Genomic Accession(s) | NG_012352, NC_000002, NC_018913 |
| UniProt ID(s) | P16422 |
| UniGene ID(s) | P16422 |
| HGNC ID(s) | 11529 |
| Cosmic ID(s) | EPCAM |
| KEGG Gene ID(s) | hsa:4072 |
| PharmGKB ID(s) | PA35493 |
| General Description of EpCAM / CD326. | |
| EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (EpCAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. | |
Limitations and Warranty
This product is for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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