.jpg "Galectin-13 IHC human Placenta (PP13 1162)")
PDF DatasheetHuman Anti-Galectin-13 Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-Galectin-13 Antibody Clone: PP13/1162
Clone PP13/1162 Host and Isotype: Mouse IgG2b
Anti-Human Galectin-13 Positive Control Sample: K-562 cells. Placenta or Spleen.
Cellular Localization of Antibody Cytoplasmic ;Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human Galectin-13 protein fragment (aa23-134)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
Galectin-13 Previously Observed Antibody Staining Patterns
| Galectin-13 General Information | |
|---|---|
| Alternate Names | |
| Galactoside-binding soluble lectin 13, placental protein 13, PP13, LGALS13 | |
| Molecular Weight | |
| 16kDa (monomer) ;32kDa (homodimer) | |
| Chromosomal Location | |
| 19q13.1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | LGALS13 |
| Entrez Gene ID | 29124 |
| Ensemble Gene ID | ENSG00000105198 |
| RefSeq Protein Accession(s) | XP_011525176, NP_037400, XP_016882204 |
| RefSeq mRNA Accession(s) | XM_017026715, XM_011526874, NM_013268 |
| RefSeq Genomic Accession(s) | NC_000019, NC_018930 |
| UniProt ID(s) | Q9UHV8 |
| UniGene ID(s) | Q9UHV8 |
| HGNC ID(s) | 15449 |
| Cosmic ID(s) | LGALS13 |
| KEGG Gene ID(s) | hsa:29124 |
| PharmGKB ID(s) | PA134923011 |
| General Description of Galectin-13. | |
| This MAb recognizes a 32kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble ?-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia. | |
Limitations and Warranty
enQuire Bio’s Galectin-13 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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